May 12, 2013 - Fund, the Knut and Alice Wallenberg Foundation and the Skåne ... Pearce EN, Farwell AP, Braverman LE (2003) Thyroiditis. N Engl.
Diabetologia (2013) 56:1735–1742 DOI 10.1007/s00125-013-2934-9
ARTICLE
Thyroid autoimmunity in relation to islet autoantibodies and HLA-DQ genotype in newly diagnosed type 1 diabetes in children and adolescents B. Jonsdottir & C. Andersson & A. Carlsson & A. Delli & G. Forsander & J. Ludvigsson & C. Marcus & U. Samuelsson & E. Örtqvist & Å. Lernmark & S.-A. Ivarsson & H. Elding Larsson & for the Better Diabetes Diagnosis (BDD) study group Received: 20 December 2012 / Accepted: 22 April 2013 / Published online: 12 May 2013 # Springer-Verlag Berlin Heidelberg 2013
Abstract Aims/hypothesis The aim of this work was to investigate, in children newly diagnosed with type 1 diabetes: (1) the prevalence of autoantibodies against thyroid peroxidase (TPOAb) and thyroglobulin (TGAb); and (2) the association between TPOAb, TGAb or both, with either islet autoantibodies or HLA-DQ genes. Methods Blood samples from 2,433 children newly diagnosed with type 1 diabetes were analysed for TPOAb and TGAb in addition to autoantibodies against arginine zinc transporter 8 (ZnT8RA), tryptophan zinc transporter 8 (ZnT8WA), glutamine zinc transporter 8 (ZnT8QA), Members of the BDD study group are listed in the Appendix. B. Jonsdottir (*) : C. Andersson : A. Delli : Å. Lernmark : S.
