Introduction: Effective prevention of osteoporotic fracture requires long term ... Results: A total of 193 patients participated in this study with 79.1 % response rate. ..... reached when the growth in the size of bones and accumulation of bone mineral has ...... Start date: ______ (dd/mm/yy) Stop date: ______(dd/mm/yy). Duration ...
Title
Author(s)
Factors associated with osteoporosis medication adherence in HongKong
Soong, Sze-sze; 宋思思
Citation
Issue Date
URL
Rights
2010
http://hdl.handle.net/10722/132312
Creative Commons: Attribution 3.0 Hong Kong License
Abstract of thesis entitled
"Factors associated with osteoporosis medication adherence in Hong Kong" Submitted by
Soong Sze Sze
for the degree of Master of Public Health at The University of Hong Kong in August 2010
Introduction: Effective prevention of osteoporotic fracture requires long term adherence to osteoporosis medication. Longitudinal studies revealed that more than 50% of patients terminated their treatment at one year and the problem increases with time. [1] The circumstance of osteoporosis medication adherence in Hong Kong is still unclear.
Objective: To assess patient adherence to osteoporosis medication in Hong Kong and to identify the associating factors. i
Method: 244 patients attended the osteoporosis clinic in Queen Mary Hospital for the first time between January 2007 and December 2008 were invited to participate in a retrospective observational study for their adherence to treatment. Baseline clinical and demographic information, bone mineral density, lifestyle risk factors were assessed by medical charts review. Details in treatment adherence, acceptance, incident fractures, hospital admission and mobility level were collected by telephone interviews. Information were verified from the Hospital Authority Electronic Patient Record System. Medication compliance was measured by proportion of days covered (PDC). A patient is considered as adherent if he/she had missed < 20% of the proportion of days covered (PDC). [2]
Results: A total of 193 patients participated in this study with 79.1 % response rate. The mean rate of medication adherence was 75.3% (PDC) (SD: 36.38) after a mean patient visit years of 2.3. The rate of medication adherence decreased progressively with longer treatment duration (PDC: 74.5% with SD: 36.64 at the first year, 75.6% with SD: 34.78 at the second year, 63.7% with SD: 40.74 at the third year). The risk factors were found as "Medication caused adverse effects" (OR: 40.73, 95% CI: 5.11-324.41, p
