Transcriptional profiling of newly generated dentate ...

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Feb 12, 2016 - tagging严) to map the profile of nascent mRNAs in mouse immature newborn. 40 granule cells ... 62 into adulthood. These newborn neurons contribute to learning and memory,. 63 ...... A Python framework to work with. 664.
This Accepted Manuscript has not been copyedited and formatted. The final version may differ from this version.

Research Article: New Research | Development

Transcriptional profiling of newly generated dentate granule cells using TU-tagging reveals pattern shifts in gene expression during circuit integration Transcriptome analysis using TU-tagging in the DG 1,*

1,*

Christina Chatzi , Gina Zhang , Rongkun Shen

1,2

1

, Gary L. Westbrook and Richard H. Goodman

1

Vollum Institute, Portland, OR, USA 97239 DOI: 10.1523/ENEURO.0024-16.2016 Received: 2 February 2016 Accepted: 4 February 2016 Published: 12 February 2016

Author contributions: G.L.W., C.C., G.Z., R.S., and R.H.G. designed research; G.L.W., C.C., G.Z., R.S., and R.H.G. performed research; G.L.W., C.C., G.Z., R.S., and R.H.G. contributed unpublished reagents/analytic tools; G.L.W., C.C., G.Z., R.S., and R.H.G. analyzed data; G.L.W., C.C., G.Z., R.S., and R.H.G. wrote the paper. Funding: DH | National Institute for Health Research (NIHR): 501100000272; NS080979. Ellison Medical Foundation; AXA Research Fund Postdoctoral Fellowship; NINDS: P30NS061800. Current address: Department of Biology, The College at Brockport, SUNY, Brockport, NY 14420 DH | National Institute for Health Research (NIHR) (501100000272). Ellison Medical Foundation. *contributed equally to this work. Address correspondence to: Gary L. Westbrook, Vollum Institute, L474, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland OR 97239. email: [email protected] Cite as: eNeuro 2016; 10.1523/ENEURO.0024-16.2016 Alerts: Sign up at eneuro.org/alerts to receive customized email alerts when the fully formatted version of this article is published.

Accepted manuscripts are peer-reviewed but have not been through the copyediting, formatting, or proofreading process. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Copyright © 2016 Society for Neuroscience

 

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