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J.P. Mitchell, M.W. Nagel, C.C. Doyle and S.L. Bates. Trudell Medical ... As expected, humidification reduced TED, but less so in the pediatric compared with the.
Vffi) X Vch_1. (3). Dead space (Vd) in valve house (or mask) re- duces the amount of aerosol inspired per breath to a fraction (Vr - Vd) X Vj_1 of the volume that.
BACKGROUND: Delivery of bronchodilator to infants and small children from a pressurized metered-dose inhaler with valved holding chamber (pMDI-VHC) is ...
J.P. Mitchell, M.W. Nagel, C.C. Doyle, S.L. Bates, K. J. Wiersema and D.K. Engelbreth ... Total emitted dose (TED) and fine particle dose ((FPD) particles < 4.7 µm.
Received 21 January 1997; accepted for publication 9 May 1997. Under routine source conditions, the optimum nozzle-skimmer distance to achieve maximum.
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A 51-year-old male was admitted to the hospital with complaints of fever and hemoptysis. After evaluation of the fever focus, he was diagnosed with pulmonary ...
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intercomparison with a cylindrical chamber in a high-energy electron beam. Finally ....
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drug delivery efficiency was similar from four commercially available VHCs, two of ... Recovered FP and SX were assayed by validated HPLC-based methods.
Use of Valved Holding Chambers Without Pre-Conditioning and the Influence of Anti-Static Materials 1
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Jason Suggett , Mark Nagel , Cathy Doyle , Heather Schneider and Jolyon Mitchell
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Trudell Medical International, 725 Third St., London, N5V 5G4, Canada Jolyon Mitchell Inhaler Consulting Services Inc., 1154 St. Anthony Rd., London, N6H 2R1, Canada
Summary Background: In recent years ‘anti-static’ Valved Holding Chambers (VHCs) have become more widely available. They enable use directly out of packet without pre-treatment, as pre-washing with detergent followed by drip-drying in air is time-consuming and not always followed. This laboratory study sought to investigate whether fine particle (