Accepted Manuscript Usefulness of SYNTAX Score II in Complex Percutaneous Coronary Interventions in the Setting of Acute Coronary Syndrome Azzarelli Salvatore, Marouane Boukhris, Simona Giubilato, Salvatore Davide Tomasello, Marine Castaing, Rocco Giunta, Francesco Marzà, Hosam Mohamad Abdelbasset, Hazem Khamis, Alfredo Ruggero Galassi PII: DOI: Reference:
S1016-7315(15)00160-8 http://dx.doi.org/10.1016/j.jsha.2015.07.003 JSHA 321
To appear in:
Journal of the Saudi Heart Association
Received Date: Revised Date: Accepted Date:
1 May 2015 10 July 2015 21 July 2015
Please cite this article as: A. Salvatore, M. Boukhris, S. Giubilato, S.D. Tomasello, M. Castaing, R. Giunta, F. Marzà, H.M. Abdelbasset, H. Khamis, A.R. Galassi, Usefulness of SYNTAX Score II in Complex Percutaneous Coronary Interventions in the Setting of Acute Coronary Syndrome, Journal of the Saudi Heart Association (2015), doi: http://dx.doi.org/10.1016/j.jsha.2015.07.003
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Usefulness of SYNTAX Score II in Complex Percutaneous Coronary Interventions in the Setting of Acute Coronary Syndrome
Azzarelli Salvatore MD1, Marouane Boukhris MD1,2 ,Simona Giubilato MD1, Salvatore Davide Tomasello MD1, Marine Castaing MSc1, Rocco Giunta MD1, Francesco Marzà MD1, Hosam Mohamad Abdelbasset MD1,3, Hazem Khamis MD, FACC4,Alfredo Ruggero Galassi MD, FESC, FACC, FSCAI1.
From:1Department of Clinical and Experimental Medicine, Catheterization Laboratory and Cardiovascular Interventional Unit, Division of Cardiology, Cannizzaro Hospital, University of Catania, Italy; 2
Faculty of Medecine of Tunis,University of Tunis El Manar, Tunisia; 3
Maadi Military Hospita, Military Medical Academy, Cairo, Egypt; 4
Cardiology Unit, October 6th University Egypt, Cairo, Egypt.
Address for correspondence: Prof. Alfredo R. Galassi, MD, FACC, FESC, FSCAI Via Antonello da Messina 75 Acicastello, 95021 Catania, Italy Tel: 0039-095-7263122-3623 Fax: +39-095-7263124-3633 website: www.alfredogalassi.com Secretariat:
[email protected] E-mail:
[email protected]
Running title: Syntax II score in complex PCI. Words account: 4834
1
ABSTRACT Background SYNTAX score II (SS II) integrates anatomical SS with clinical characteristics allowing an individualized prediction of long-term mortality.
Aims We sought to assess to evaluate the usefulness of SS II in a real world acute coronary syndromes (ACS) population with severe coronary artery disease (CAD), undergoing percutaneous coronary intervention (PCI).
Methods From August 2011 to May 2013, out of 1591 consecutive patients admitted for ACS, 217 (13.6%) showed severe CAD (3-vessel disease and/or left main involvement). Among these latter, 100 patients underwent PCI and were enrolled into the study. SS II was calculated in all patients. One-year clinical follow-up was performed; major adverse cardiac and cerebrovascular events (MACCE) were defined as a composite of death, non-fatal myocardial infarction (MI), stroke, or repeat revascularization.
Results The median SS II was 29 (ranges 14-59).Overall, MACCE occurred in 25% of patients (cardiac death 4%, MI 4%, stroke 0%, and repeat revascularization 17%). The 1-year MACCE-free survival was significantly lower in patients with SS ≥29 than in those with SS II
