vaccine vol. 21 no. 11-12 march; 2003

VACCINE VOL. 21 NO. 11-12 MARCH; 2003 REGULAR PAPERS Expression, polymorphism analysis, reticulocyte binding and serological reactivity of two Plasmodium vivax MSP-1 protein recombinant fragments Ana María Espinosa, Adriana Yanett Sierra, Carlos Alberto Barrero, Libia Alexandra Cepeda, Elvia María Cantor, Tania Bibiana Lombo, Fanny Guzmán, Sandra Julieta Avila and Manuel Alfonso Patarroyo MMR vaccination advice over the Internet, Pages Katja Schmidt and Edzard Ernst `Clustering of exemptions' as a collective action threat to herd immunity, Thomas May and Ross D. Silverman Vaccination against type F botulinum toxin using attenuated Salmonella enterica var Typhimurium strains expressing the BoNT/F HC fragment, Susan Foynes, Jane L. Holley, Helen S. Garmory, Richard W. Titball and Neil F. Fairweather Reduction of -amyloid plaques in brain of transgenic mouse model of Alzheimer's disease by EFRH-phage immunization Dan Frenkel, Ilse Dewachter, Fred Van Leuven and Beka Solomon HIV-specific immunity during structured antiviral drug treatment interruption* Ronald B. Moss, Carolyn Brandt, Wieslawa K. Giermakowska, Jay R. Savary, Georgia Theofan, Maurizio Zanetti, Dennis J. Carlo and Mark R. Wallace The out of Africa model of varicella-zoster virus evolution: single nucleotide polymorphisms and private alleles distinguish Asian clades from European/North American clades Timothy R. Wagenaar, Vincent T. K. Chow, Chantanee Buranathai, Pranee Thawatsupha and Charles Grose Eradication of established HPV16-transformed tumours after immunisation with recombinant Semliki Forest virus expressing a fusion protein of E6 and E7 Toos Daemen, Annelies Riezebos-Brilman, Laura Bungener, Joke Regts, Bert Dontje and Jan Wilschut DNA immunization with pgp3 gene of Chlamydia trachomatis inhibits the spread of chlamydial infection from the lower to the upper genital tract in C3H/HeN mice Manuela Donati, Vittorio Sambri, Maurizio Comanducci, Korinne Di Leo, Elisa Storni, Lorenzo Giacani, Giulio Ratti and Roberto Cevenini Seroprevalence of meningococcal serogroup C bactericidal antibody in England and Wales in the pre-vaccination era Caroline Trotter, Ray Borrow, Nick Andrews and Elizabeth Miller Vaccination of puppies with a lipid-formulated plasmid vaccine protects against a severe canine distemper virus challenge Laurent Fischer, Jean Philippe Tronel, Jules Minke, Simona Barzu, Philippe Baudu and Jean-Christophe Audonnet

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Immunization with low doses of HIV-1 tat DNA delivered by novel cationic block copolymers induces CTL responses against Tat Antonella Caputo, Riccardo Gavioli, Giuseppe Altavilla, Egidio Brocca-Cofano, Chiara Boarini, Monica Betti, Arianna Castaldello, Franco Lorenzini, Fabiola Micheletti, Aurelio Cafaro et al. Construction of designer glycoconjugate vaccines with size-specific oligosaccharide antigens and site-controlled coupling Julia Y. Wang, Alex H. C. Chang, Hilde-Kari Guttormsen, Angel L. Rosas and Dennis L. Kasper Total genome polymorphism and low frequency of intra-genomic variation in the uspA1 and uspA2 genes of Moraxella catarrhalis in otitis prone and non-prone children up to 2 years of age: Consequences for vaccine design? John P. Hays, Cindy van der Schee, Anita Loogman, Kim Eadie, Cees Verduin, Howard Faden, Henri Verbrugh and Alex van Belkum Immunisation with modified HPV16 E7 genes against mouse oncogenic TC-1 cell sublines with downregulated expression of MHC class I molecules Michal mahel, Pavel íma, Viera Ludvíková, Iuri Marinov, Dana Pokorná and Vladimír Vonka Influenza vaccine uptake in the elderly: results from a rapid assessment of the effectiveness of new government policy in England for the winters Carol Joseph and Nichola Goddard Ginseng and aluminium hydroxide act synergistically as vaccine adjuvants E. Rivera, S. Hu and C. Concha Rapid onset of protection following vaccination of calves with multivalent vaccines containing modified-live or modified-live and killed BHV-1 is associated with virus-specific interferon gamma production Amelia R. Woolums, Leonardo Siger, Scott Johnson, Guillermo Gallo and Jennifer Conlon Mucosal and systemic antibody responses against an acellular pertussis vaccine in mice after intranasal co-administration with recombinant cholera toxin B subunit as an adjuvant Masanori Isaka, Yoko Yasuda, Tooru Taniguchi, Satoshi Kozuka, Keiko Matano, Jun-ichi Maeyama, Kazunori Morokuma, Kunio Ohkuma, Norihisa Goto and Kunio Tochikubo Revaccination of healthy nonresponders with hepatitis B vaccine and prediction of seroprotection response*1 Myong-Jin Kim, Anne N. Nafziger, Clayton D. Harro, Harry L. Keyserling, Keith M. Ramsey, George L. Drusano and Joseph S. Bertino, Jr. Local and systemic immune response in nursing-home elderly following intranasal or intramuscular immunization with inactivated influenza vaccine Mordechai Muszkat, Evgenia Greenbaum, Arie Ben-Yehuda, Moses Oster, Efrain Yeu'l, Shmuel Heimann, Reuven Levy, Gideon Friedman and Zichria Zakay-Rones

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Enhancing the immunogenicity of bioengineered Listeria monocytogenes by passaging through live animal hosts Christian Peters and Yvonne Paterson Expression and immunogenicity of the major house dust mite allergen Der p 1 following DNA immunization Claudia Betina Wolfowicz, TaoQi HuangFu and Kaw Yan Chua Immunity to East Coast fever in cattle induced by a polypeptide fragment of the major surface coat protein of Theileria parva sporozoites Richard Bishop, Vishvanath Nene, Jan Staeyert, John Rowlands, John Nyanjui, Julius Osaso, Subhash Morzaria and Antony Musoke Carrier-dependent specificity of antibodies to a conserved peptide determinant of gp120 S. Karle, Y. Nishiyama, H. Taguchi, Y. -X. Zhou, J. Luo, S. Planque, C. Hanson and S. Paul Relationship between the degree of antigen adsorption to aluminum hydroxide adjuvant in interstitial fluid and antibody production Seema Iyer, Harm HogenEsch and Stanley L. Hem Safety and immunogenicity of a live-attenuated influenza vaccine blended and filled at two manufacturing facilities Terry Nolan, Min-Shi Lee, Julie M. Cordova, Iksung Cho, Robert E. Walker, Marilyn J. August, Susan Larson, Kathleen L. Coelingh and Paul M. Mendelman Recombinant raccoon pox vaccine protects mice against lethal plague Jorge E. Osorio, Tim D. Powell, Rexann S. Frank, Kelley Moss, Elizabeth J. Haanes, Susan R. Smith, Tonie E. Rocke and Dan T. Stinchcomb Co-immunization with plasmids coding the full length and a soluble form of glycoprotein D of HSV-2 induces protective cellular and humoral immune response in mice Juan Fló Factors affecting the compliance of the antenatal hepatitis B screening programme in Italy Tommaso Stroffolini, Elvira Bianco, Andrè Szklo, Rossana Bernacchia, Crescenzo Bove, Mario Colucci, Rosa Cristina Coppola, Paolo D'Argenio, Pierluigi Lopalco, Antonino Parlato et al. Encapsulation of peptides in biodegradable microspheres prolongs their MHC class-I presentation by dendritic cells and macrophages in vitro Régine Audran,Katrin Peter, Jens Dannull, Ying Men, Elke Scandella, Marcus Groettrup, Bruno Gander and Giampietro Corradin The cost-effectiveness of routine childhood varicella vaccination in Germany*1 K. Banz, S. Wagenpfeil, A. Neiss, A. Goertz, U. Staginnus, J. Vollmar and P. Wutzler Comparison of the reactogenicity and immunogenicity of a split and a subunit-adjuvanted influenza vaccine in elderly subjects S. Squarcione, S. Sgricia, L. R. Biasio and E. Perinetti In ovo delivery of DNA to the avian embryo*1 Gretchen L. Oshop, S. Elankumaran, Vikram N. Vakharia and Robert

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A. Heckert Construction and characterisation of O139 cholera vaccine candidates Talena Ledón, Edgar Valle, Tania Valmaseda, Barbara Cedré, Javier Campos, Boris L. Rodríguez, Karen Marrero, Hilda García, Luis García and Rafael Fando Vaccination with DNA encoding ORFF antigen confers protective immunity in mice infected with Leishmania donovani Bindu Sukumaran, Poonam Tewary, Shailendra Saxena and Rentala Madhubala Dendritic Cell Protocols: S.P. Robinson and A.J. Stagg (Eds.), Methods in Molecular Medicine, vol. 64, Humana Press, New Jersey, USA, 2001, US$ 125, 470 pp., ISBN: 0-89603-584-0, Pages T. Lazar

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VOL. 21 NO. 13-14 MARCH; 2003 LETTER TO THE EDITOR Author response to letter to the editor by Marciani et al. Gui Liu and Charlotte R. Kensil Introduction of a HIV vaccine in developing countries: social and cultural dimensions P. H. Streefland Combined hepatitis B vaccines*1, Pages David FitzSimons, Guido François, Nedret Emirolu and Pierre Van Damme Protein vaccination with the HER2/neu extracellular domain plus antiHER2/neu antibody–cytokine fusion proteins induces a protective antiHER2/neu immune response in mice Jay S. Dela Cruz, Suk Ying Lau, Ernesto M. Ramirez, Carla De Giovanni, Guido Forni, Sherie L. Morrison and Manuel L. Penichet Protective effect of a naked DNA vaccine cocktail against lethal toxoplasmosis in mice Alberto Fachado, Alexandro Rodriguez, Sergio O. Angel, Diamar C. Pinto, Iviane Vila, Armando Acosta, Regina R. Amendoeira and Joseli Lannes-Vieira Longevity of antibody and cytokine responses following vaccination with high potency emergency FMD vaccines S. J. Cox, N. Aggarwal, R. J. Statham and P. V. Barnett Adverse medical events in British service personnel following anthrax vaccination Joanne E. Enstone, Martin C. J. Wale, Jonathan S. Nguyen-Van-Tam and James C. G. Pearson Immunity to avian pneumovirus infection in turkeys following in ovo vaccination with an attenuated vaccine Karen J. Worthington, Barbara A. Sargent, F. G. Davelaar and R. C. Jones Super-activated interferon-regulatory factors can enhance plasmid immunization Jonathan L. Bramson, Kelley Dayball, Jennifer R. Hall, James B. Millar, Mark Miller, Yong Hong Wan, Rongtuan Lin and John Hiscott Cold adapted avian pneumovirus for use as live, attenuated vaccine in

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turkeys Devi P. Patnayak, Baldev R. Gulati, Anwar M. Sheikh and Sagar M. Goyal Protection against a European H1N2 swine influenza virus in pigs previously infected with H1N1 and/or H3N2 subtypes Kristien Van Reeth, Vicki Gregory, Alan Hay and Maurice Pensaert Smallpox vaccination techniques: 2. Accessories and aftercare Derrick Baxby Improvement of the systemic prime/oral boost strategy for systemic and local responses Tosca G. M. Lauterslager, Wil Stok and Luuk A. T. Hilgers Chitosan microparticles for mucosal vaccination against diphtheria: oral and nasal efficacy studies in mice, Pages Inez M. van der Lubben, Gideon Kersten, Marjan M. Fretz, Coen Beuvery, J. Coos Verhoef and Hans E. Junginger Development of a foot-and-mouth disease NSP ELISA and its comparison with differential diagnostic methods Chang Hee Kweon, Young Joon Ko, Won II Kim, Se Young Lee, Jin Ju Nah, Kwang Nyeong Lee, Hyun Joo Sohn, Kang Seuk Choi, Bang Hun Hyun, Seung Won Kang et al. Protective immunity against pasteurellosis in cattle, induced by Pasteurella haemolytica ghosts J. Marchart, M. Rehagen, G. Dropmann, M. P. Szostak, S. Alldinger, S. Lechleitner, T. Schlapp, S. Resch and W. Lubitz Vaccines for children: policies, politics and poverty S. K. Obaro and A. Palmer Gene gun-based co-immunization of merozoite surface protein-1 cDNA with IL-12 expression plasmid confers protection against lethal Plasmodium yoelii in A/J mice Tohru Sakai, Hajime Hisaeda, Yoko Nakano, Manxin Zhang, Miwa Takashima, Kazunari Ishii, Yoichi Maekawa, Soukichi Matsumoto, Yoshio Nitta, Jun-ichi Miyazaki et al. Modulation of dendritic cell endocytosis and antigen processing pathways by Escherichia coli heat-labile enterotoxin and mutant derivatives Liljana Petrovska, Luciene Lopes, Cameron P. Simmons, Mariagrazia Pizza, Gordon Dougan and Benjamin M. Chain Immunization with the Chlamydia trachomatis major outer membrane protein, using the outer surface protein A of Borrelia burgdorferi as an adjuvant, can induce protection against a chlamydial genital challenge, Pages Sukumar Pal, Catherine J. Luke, Alan G. Barbour, Ellena M. Peterson and Luis M. de la Maza Innate immune responses following emergency vaccination against foot-and-mouth disease virus in pig R. C. Rigden, C. P. Carrasco, P. V. Barnett, A. Summerfield and K. C. McCullough Nasal delivery of chitosan–DNA plasmid expressing epitopes of respiratory syncytial virus (RSV) induces protective CTL responses in BALB/c mice

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M. Iqbal, W. Lin, I. Jabbal-Gill, S. S. Davis, M. W. Steward and L. Illum Sensitivity and specificity of patient self-report of influenza and pneumococcal polysaccharide vaccinations among elderly outpatients in diverse patient care strata Richard Kent Zimmerman, Mahlon Raymund, Janine E. Janosky, Mary Patricia Nowalk and Michael J. Fine Identification of protective antigens for the control of Ixodes scapularis infestations using cDNA expression library immunization Consuelo Almazán, Katherine M. Kocan, Douglas K. Bergman, Jose C. Garcia-Garcia, Edmour F. Blouin and José de la Fuente Induction of specific T-helper and cytolytic responses to epitopes displayed on a virus-like protein scaffold derived from the pyruvate dehydrogenase multienzyme complex Gonzalo J. Domingo, Antonella Caivano, Rossella Sartorius, Pasquale Barba, Malin Bäckström, Dominique Piatier-Tonneau, John Guardiola, Piergiuseppe De Berardinis and Richard N. Perham Barriers and facilitators of pneumococcal vaccination among the elderly*1 Richard Kent Zimmerman, Tammy A. Santibanez, Michael J. Fine, Janine E. Janosky, Mary Patricia Nowalk, Inis Jane Bardella, Mahlon Raymund and Stephen A. Wilson Immune responses of elk to Mycobacterium bovis bacillus Calmette Guerin vaccination W. R. Waters, M. V. Palmer, S. C. Olsen, R. E. Sacco and D. L. Whipple Rectal immunization of mice with hepatitis A vaccine induces stronger systemic and local immune responses than parenteral immunization, Leslie Ann Mitchell and Eithan Galun Effect of vaccine delivery system on the induction of HPV16L1specific humoral and cell-mediated immune responses in immunized rhesus macaques Timothy W. Tobery, Judith F. Smith, Nelly Kuklin, DeeMarie Skulsky, Christopher Ackerson, Lingyi Huang, Ling Chen, James C. Cook, William L. McClements and Kathrin U. Jansen The role of lipopolysaccharide in T-cell responses following DNA vaccination William G. Hawkins, Jiri Trcka, Neil Segal, Nathalie E. Blachere, Jason S. Gold, Yoichi Moroi, Wilbur B. Bowne, Jonathan J. Lewis, Jedd D. Wolchok and Alan N. Houghton Non-interference between two protein carriers when used with the same polysaccharide for pneumococcal conjugate vaccines in 2-yearold children Porter Anderson, John Treanor, Susan Porcelli and Michael Pichichero

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VOL. 21 NO.SUPPLEMENT 1 APRIL 2003 TICK-BORNE ENCEPHALITIS: VIRUS, DISEASE, AND PREVENTION Tick-Borne Encephalitis: Virus, Disease, and Prevention Edited by: C. Kunz and F. X. Heinz Tick-borne encephalitis––pathogenesis, clinical course and long-term

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follow-up Mats Haglund and Göran Günther Tick-borne encephalitis C. Kunz and F. X. Heinz Report of the Meningitis Program of the International Scientific Working Group on TBE: Serological screening of patients with viral CNS-infection of unknown etiology in search of undiagnosed TBE cases Mats Haglund, Bo Settergren, Franz X. Heinz, Göran Günther and The ISW–TBE Study Group Social marketing and the establishment of the ISW-TBE Michael Kunze and Ursula Kunze Epidemiology and ecology of TBE relevant to the production of effective vaccines Jochen Süss TBE vaccination and the Austrian experience Christian Kunz History of TBE vaccines P. Noel Barrett, Susanne Schober-Bendixen and Hartmut J. Ehrlich A controlled trial of tick-borne encephalitis vaccination in patients with multiple sclerosis Ulf Baumhackl, Claudia Franta, Johann Retzl, Erich Salomonowitz and Gerald Eder The Austrian TBE Patient Support Group T. Pisecky and C. Freund Diagnosis of tick-borne encephalitis Heidemarie Holzmann Molecular aspects of TBE virus research Franz X. Heinz

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VOL. 21 NO. 16 MAY; 2003 Influenza Vaccine Editorial A. D. M. E. Osterhaus REGULAR PAPERS The Global Agenda on Influenza Surveillance and Control Klaus Stöhr The evolution of influenza surveillance in Europe and prospects for the next 10 years D. M. Fleming, J. van der Velden and W. J. Paget Animal influenza virus surveillance Ron A. M. Fouchier, Albert D. M. E. Osterhaus and Ian H. Brown Applications of bioinformatics and computational biology to influenza surveillance and vaccine strain selection Derek J. Smith The epidemiology and clinical impact of pandemic influenza Jonathan S. Nguyen-Van-Tam and Alan W. Hampson The efficacy, effectiveness and cost-effectiveness of inactivated influenza virus vaccines Kristin L. Nichol

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The annual production cycle for influenza vaccine Catherine Gerdil Influenza vaccination in 2000: recommendations and vaccine use in 50 developed and rapidly developing countries G. A. van Essen, A. M. Palache, E. Forleo and D. S. Fedson The influenza vaccine licensing process J. M. Wood and R. A. Levandowski Novel generations of influenza vaccines George Kemble and Harry Greenberg The role of antivirals in the control of influenza Arnold S. Monto Influenza pandemic planning Nancy J. Cox, Susan E. Tamblyn and Theresa Tam

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