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Ndam et al. SpringerPlus (2016) 5:264 DOI 10.1186/s40064-016-1928-8

RESEARCH

Open Access

Phytochemical analysis, antimicrobial and antioxidant activities of Euphorbia golondrina L.C. Wheeler (Euphorbiaceae Juss.): an unexplored medicinal herb reported from Cameroon Lawrence Monah Ndam1*, Afui Mathias Mih1, Aaron Suh Tening2, Augustina Genla Nwana Fongod1, Nkegua Anna Temenu3 and Yoshiharu Fujii4 *Correspondence: [email protected] 1 Department of Botany and Plant Physiology, University of Buea, P.O. Box 63, Fako, South West Region, Cameroon Full list of author information is available at the end of the article

Abstract  This study aimed at determining the phytochemical constituents of Euphorbia golondrina L.C. Wheeler, an alien invasive medicinal herb that is used for the treatment of gastroenteritis related ailments, diabetes, conjunctivitis, gastritis, enterocolitis, tonsil‑ litis, vaginitis, hemorrhoids, prostatism, warts and painful swellings by the Mundani people of the mount Bambouto Caldera in SouthWestern Cameroon, and to evaluate its in vitro antimicrobial and antioxidant activities. Susceptibility testing by agar well diffusion assay revealed good antibacterial activity with inhibition zone diameter of 20 ± 1.1 mm against Bacillus cereus followed by Staphylococcus aureus with inhibition zone diameter of 17 ± 1.6 mm which was significantly lower (P