X Chromosome Dosage Influences DNA Methylation Dynamics during ...

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Vincent Pasque, Rahul Karnik, Constantinos Chronis, Paula Petrella, Justin. Langerman, Giancarlo Bonora, Juan Song, Lotte Vanheer, Anupama Sadhu.
Stem Cell Reports, Volume 10

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X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs Vincent Pasque, Rahul Karnik, Constantinos Chronis, Paula Petrella, Justin Langerman, Giancarlo Bonora, Juan Song, Lotte Vanheer, Anupama Sadhu Dimashkie, Alexander Meissner, and Kathrin Plath

Female XO iPSCs

4 4 17 Female XaXa iPSCs

8 8 11 2

Female iPSC line 8

Female iPSC line 7

Female iPSC line 9

Female iPSC line 10

Female iPSC line 6

Female iPSC line 5

Passage number: Female iPSC line 4

% biallelic Tsix

Female iPSC line 3

Figure S1

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Male ESCs

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Female MEFs

50% 25% 0% 100% 75%

Female SSEA1-

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