Yaling Liu - Lehigh University

YALING LIU Mechanical Engineering and Mechanics Bioengineering Program Lehigh University Website : http://www.lehigh.edu/~yal310

A. BIOGRAPHICAL INFORMATION Business Address: Office Phone: Office Fax: E-mail: Position: Affiliation:

19 Memorial Drive West, Bethlehem, PA 18015, USA (610) 758-5238 (610) 758-6224 [email protected] Associate Professor Mechanical Engineering and Mechanics, Bioengineering Program, Lehigh University

EDUCATION Northwestern University, Evanston, IL Ph.D. in Mechanical Engineering, Dec 2006 Dissertation: Integrated Simulation Tools for Fluid-Structure Interactions in Bio-Nano Systems Advisor: Prof. Wing Kam Liu Northwestern University, Evanston, IL M.S. in Mechanical Engineering, Dec 2004 Tsinghua University, Beijing, China B.S. in Engineering Mechanics, July 2001 PROFESSIONAL EXPERIENCE Associate Professor (with Tenure) Mechanical Engineering and Mechanics, Lehigh University Bioengineering Program, Lehigh University

05/2013-Present 05/2013-Present

P.C. Rossin Assistant Professor Mechanical Engineering and Mechanics, Lehigh University Bioengineering Program, Lehigh University

08/2010-05/2013 08/2010-05/2013

Assistant Professor Mechanical and Aerospace Engineering, the University of Texas at Arlington 09/2007-08/2010 Graduate Committee Member, Joint Program in Biomedical Engineering, UTA-UT Southwestern Medical Center 09/2007-08/2010 Senior Product Engineer Mechanical Research and Development, Seagate Technologies, MN

06/2006-08/2007

B. PUBLICATIONS AND CREATIVE ACTIVITIES B.1. CHAPTERS IN BOOKS 1. Y. Liu, J. Yang, Y. Zou, J. Hu, “Mechanics and Structural Design of Vascular Stents”, Multiscale 5

Simulation and Mechanics of Biological Materials, Wiley, 2012 2. Y. Liu, A. Ramachandran, Q. Guo, “Coarse-Grained Modeling of DNA-Nanopore Interaction and Drug Delivery”, Simulations in Nanobiotechnology, Taylor & Francis, 2011 3. W. K. Liu, A. Karpov, Y. Liu, “Computational Nanomechanics”, Handbook of Nanophysics, Taylor & Francis, 2010 4. W.K. Liu, E. Karpov, H. Park, Nano Mechanics and Materials: Theory, Multiscale Methods and Applications, John Wiley and Sons, 2006. Y. Liu contributed chapter 10 entitled “Bio-Nano Interface” 5. W.K. Liu, Y. Liu, A. Gerstenberger, D. Farrell, L. Zhang and X. Wang, “Immersed Finite Element Method and applications to Biological systems”, in Finite Element Methods: 1970’s and Beyond, CIMNE, 2004 6. S. Li and W.K. Liu, Meshfree Particle Methods, Springer, 2004. “Immersed Meshfree Finite Element Method and Applications”

Y. Liu contributed chapter 12 entitled

7. D. Qian, G.J. Wagner, W.K. Liu, M.F. Yu, Y. Liu, and R.S. Ruoff, “Mechanics and mechanical application of carbon nanotubes”, Encyclopedia of Nanoscience and Nanotechnology, American Scientific Publishers, 2003 B.2. REFEREED JOURNAL ARTICLES 1.

W.J. Keller, J. Tan, Y. Liu, “A Coupled Lattice Boltzmann-XFEM Model for Evaluating Crack Detection Methods for Fluid-Structure Interaction Applications”, Computer Methods in Applied Mechanics and Engineering, submitted, 2016

2.

R. He, S. Wang, G. Andrews, W. Shi, Y. Liu, “Generation of Customizable Micro-wavy Pattern through Grayscale Direct Image Lithography”, Scientific Reports, in press, 2016

3.

S. Wang, S. Yang, X. Chen, Y. Liu, “Highly Efficient and Selective Isolation of Circulating Tumor Cells Using a Microfluidic Chip with Wavy-herringbone Micro-patterned Surfaces”, Analyst, in press, 2016

4.

J. Tan, W. Keller, S. Sohrabi, J. Yang, Y. Liu, “Characterization of Nanoparticle Dispersion in Red Blood Cell Suspension by Lattice Boltzmann–Immersed Boundary Method”, in press, Nanomaterials, 2016

5.

A. Thomas, C. Orr, D. Ou-Yang, L. Lorentz, V. Muzkantov, Y. Liu, “Biomimetic Channel Modeling Local Vascular Dynamics of Pro-inflammatory Endothelial Changes”, Biomicrofluidics, 10, 014101, 2016

6.

C. E Clancy, G. An, W. R Cannon, Y. Liu, E. E May, P. Ortoleva,A. Popel, J. P Sluka, J. Su,P. Vicini, X. Zhou, D. M Eckmann, “Multiscale Modeling in the Clinic: Drug Design and Development”, Annals of Biomedical Engineering, in press, 2016

7.

W. Shi, R. He, Y. Liu, “3D Printing Scaffolds with Hydrogel Materials for Biomedical Applications”, European Journal of BioMedical Research, 1(3): 3-8, 2015

8.

Y. Zhou, S. Sohrabi. J. Tan, Y. Liu, “Mechanical Properties of Nanoworm Assembled by DNA and Nanoparticle Conjugates”, Journal of Nanoscience and Nanotechnology, in press, 2015

9.

J.W. Myerson, A. C. Anselmo, Y. Liu, S. Mitragotri, D. M. Eckmann, V. R. Muzykantov, “Non-affinity Factors Modulating Vascular Targeting of Nano- and microcarriers”, Advanced Drug Delivery Reviews, in press, 2015

10. B. Peng, Y. Liu, Y. Zhou, L. Yang, G. Zhang, Y. Liu, “Modeling Nanoparticle Targeting to a Vascular 5

Surface in Shear Flow Through Diffusive Particle Dynamics”, Nanoscale Research Letters, 10:235, 2015 11. Z. Wang, K. Wang, X. Lu, C. Li, L. Han, C. Xie, Y. Liu, S. Qu, G. Zhen, “Nanostructured Architectures by Assembling Polysaccharide-Coated BSA Nanoparticles for Biomedical Application”, Advanced Healthcare Materials, 4(6):927-37, 2015. 12. J. Hu, Y. Liu, “Cyclic Strain Enhances Cellular Uptake of Nanoparticles”, Journal of Nanomaterials, 2015 (953584), 2015 13. Q. Wang, M Wang, K. Wang, Y. Liu, H. Zhang, X. Lu, X. Zhang, “Computer Simulation of Biomolecule–Biomaterial Interactions at Surfaces and Interfaces”, Biomedical Materials, 10, 032001, 2015 14. J. Hu, A. C. Hardy, A. Voloshin, S. Yang, Y. Liu, “Endothelial Cell Adhesion and Alignment on a Wavy Surface”, PLOS ONE, 9(8), 2014 15. S. Sohrabi, J. Zheng, E. A. Finol, Y. Liu, “Numerical Simulation of Particle Transportation and Deposition in Pulmonary Vasculature”, Journal of Biomechanical Engineering, 136(12), 121010, 2014 16. S. Wang, Y. Wan, Y. Liu, “Effects of Nanopillar Array Diameter and Spacing on Cancer Cell Capture and Cell Behaviors”, Nanoscale, 6 (21): p. 12482-12489, 2014 (selected as the Front Cover story of Issue 21) 17. A. Thomas, J. Tan, Y. Liu, “Characterization of Nanoparticle Delivery in Microcirculation through a Microfluidic Device”, Microvascular Research, 94: p. 17-27, 2014 18. E. Yalcintas, J. Hu, Y. Liu and A. Voloshin, “Modeling Cell Spreading and Alignment on Micro-wavy Surfaces”, CMES: Computer Modeling in Engineering & Sciences, 98(2): p. 151-180, 2014 19. B. Peng, W. He, X. Hao, Y. Liu, “Interfacial Thermal Conductance and Thermal Accommodation Coefficient of Evaporating Thin Liquid Films: A Molecular Dynamics Study”, Computational Materials Science, 87:260-266, 2014 20. S. Wang, Y. Zhou, J. Tan, J. Yang, Y. Liu, “Computational modeling of Magnetic Nanoparticle Targeting to Stent Surface under High Gradient Field”, Computational Mechanics, 53:403-412, 2014 21. J. Tan, S. Wang, J. Yang, and Y. Liu, “Coupled Particulate and Continuum Model for Nanoparticle Targeted Delivery”, Computers and Structures, 122: 128-134, 2013. 22. J. Tan, S. Shah, A. Thomas, D. Ou-Yang, Y. Liu, “The Influence of Size, Shape and Vessel Geometry on Nanoparticle Distribution”, Microfluidics and Nanofluidics, 14(1), 77-87, 2013 23. Y. Wan§, Y. Liu§, P. B. Allen, W. Asghar, M. A. I. Mahmood, J. Tan, H. Duhon, Y.-t. Kim, A. D. Ellington and S. M. Iqbal, “Capture, Isolation and Release of Cancer Cells with Aptamer-functionalized Glass Bead Array”, Lab on a Chip, 12, 4693–4701, 2012 (§These authors contributed equally to this work, also selected as featured article in issue 12) 24. Y. Liu, S. Wang, Y. Song, J. Yang, “Biospecies Capture and Detection at Low Concentration”, Micro and Nanosystems, invited review, 4(19), 254-272, 2012 25. Y. Liu, Q. Guo, S. Wang, and W. Hu, “Electrokinetic Effects on Detection Time of Nanowire Biosensor”, Applied Physics Letters, 100, 153502, 2012 (Also selected for publication in the Virtual Journal of Nanoscale Science and Technology, April 23, 2012 issue, and Virtual Journal of Biological Physics Research April 15, 2012 issue). 26. Y. Liu, S. Shah, and J. Tan, “Computational Modeling of Nanoparticle Targeted Drug Delivery”, Reviews in Nanoscience and Nanotechnology, 1, 66-83, 2012 5

27. S. Kona, J.F Dong, Y. Liu, and K. T. Nguyen, “Biodegradable Nanoparticles Mimicking Platelet Binding Facilitate Targeted Drug Delivery to Endothelial Cells under Shear Flow”, International Journal of Pharmaceutics, 423(2), 516-524, 2012 28. J. Tan, A. Thomas, and Y. Liu, “Influence of Red Blood Cells on Nanoparticle Targeted Delivery in Microcirculation”, Soft Matter, 8 (6), 1934-1946, 2012 29. Y. Liu, J. Tan, A. Thomas, D. Ou-Yang, V. Muzykantov, “The Shape of Things to Come: Importance of Design in Nanotechnology for Drug Delivery”, Therapeutic Delivery, 3(2), 181-194, 2012 30. Y. Wan, J. Tan, W. Asghar, Y. Kim, Y. Liu, and S. M. Iqbal, “Velocity Effect on Aptamers-based Circulating Tumor Cell Isolation in Microfluidic Devices”, Journal of Physical Chemistry B, 115 (47), pp 13891–13896, 2011 31. R. Tian, S. Regonda, J.Gao, Y. Liu, Walter Hu, "Ultrasensitive Protein Detection Using Lithographically Defined Si Multi-nanowire Field Effect Transistors”, Lab on a Chip, 11, 1952-1961, 2011 32. T. Li, W. Hu, Y. Liu, B.D. Sumer, and J. Gao, "Shape-specific Polymeric Nanomedicine: Emerging Opportunities and Challenges", Experimental Biology and Medicine, 236(1), pp 20-29, 2011 33. A. Ramachandran, Q. Guo, Y. Liu, “Coarse-Grained Molecular Dynamics Simulation of DNA Translocation in Chemically-Modified Nanopores”, Journal of Physical Chemistry B, 115(19):6138-48, 2011 34. W. Yeo, K. Lee, Q. Guo, Y. Liu, J. Chung, “Ion Diffusion and DNA Stretching in an Open Nanofluidic System”, Journal of Nanotechnology in Engineering and Medicine, 2(1),pp 011004, 2011 35. S. Shah, Y. Liu*, W. Hu, J. Gao, “Modeling Particle Shape-Dependent Dynamics in Nanomedicine”, Journal of Nanoscience and Nanotechnology, 11(2), pp. 919-928, 2011 36. J. Yang, M. Liang, N. Huang, Y. Liu, “Studying the Non-uniform Expansion of a Stent Influenced by the Balloon”, Journal of Medical Engineering and Technology, 35(5-6):301-5., 2010 37. Y. Liu and S. Iqbal, “A Mesoscale Model for DNA Interaction in Functionalized Nanopores”, Applied Physics Letters, 95, 223701, 2009. Selected as the Cover Article of Nov. 30 Issue. (Also selected for publication in the Virtual Journal of Nanoscale Science and Technology, Dec 14, 2009; Virtual Journal of Biological Physics Research, Dec 1, 2009). 38. W. Yeo, J. Chung, Y. Liu, and K. Lee, “Size-Selective Concentration of DNA to a Nanostructured Tip Using Dielectrophoresis and Capillary Action”, Journal of Physical Chemistry B, 113 (31), pp 10849–10858, 2009 39. Y. Liu and S. Iqbal, “Silicon-based Novel Bio-sensing Platforms at the Micro and Nano Scale”, Electrochemical Society Transactions, 16 (15), pp. 25-45, 2009. 40. W. Yeo, J. Chung, S. Liu, Y. Liu, and K. Lee, “Rapid Detection of Mycobacterium Tuberculosis Cells by Using Microtip-Based Immunoassay”, Analytical and Bioanalytical Chemistry, 393(6-7)，pp 1593-600, 2009 41. A. Ramachandran, Y. Liu*, W. Asghar, S. Iqbal, “Characterization of DNA-Nanopore Interaction by Molecular Dynamics”, American Journal of Biomedical Science, 1(4), pp 344-351, 2009 42. Y. Liu, K. Oh, J.G. Bai, C. Chang, W. Yeo, J. Chung, K. Lee, W.K. Liu, “Manipulation of Nanoparticles and Biomolecules by Electric Field and Surface Tension”, Computer Methods in Applied Mechanics and Engineering, 197, pp 2156–2172, 2008. 5

43. K. Oh, J. Chung, J. Riley, Y. Liu, and W.K. Liu, “Fluid Flow Assisted Dielectrophoretic Assembly of Nanowires”, Langmuir, 23 (23), pp 11932 -11940, 2007 44. Y. Liu, W.K. Liu, N. Patankar, and T. Belytschko, “Immersed Electrokinetic Finite Element Method”, International Journal for Numerical Methods in Engineering, 71, pp 379-405, 2007. 45. Y. Liu and W.K. Liu, “Rheology of Red Blood Cell Aggregation in Capillary by Computer Simulation”, Journal of Computational Physics, 220 (1), pp 139-154, 2006 46. W.K. Liu, Y. Liu, and D. Farrell et al, “I mmersed Finite Element Method and Applications to Biological Systems”, Computer Methods in Applied Mechanics and Engineering, 195(1722-1749), 2006 (listed #1 in top 25 hottest articles in CMAME by Science Direct's TOP25, Jan-Mar 2006; most downloaded papers in CMAME from 2006-2008; One of ten most highly cited papers in CMAME from 2005-2008) 47. Y. Liu, J. Chung, W.K. Liu, and R. Ruoff, “Dielectrophoretic Assembly of Nanowires”, Journal of Physical Chemistry B, 110 (29), pp 14098-14106, 2006 48. Y. Liu, L. Zhang, X. Wang, and W.K. Liu, “Coupling of Navier–Stokes Equations with Protein Molecular Dynamics and Its Application to Hemodynamics”, International Journal for Numerical Methods in Fluids, 46(1237-1252), 2004

C. Honors and Awards 

P. C. Rossin Assistant Professorship, 2012-2014



National Science Foundation NSF CAREER Award, 2010-2014



Ralph E. Powe Junior Faculty Enhancement Award, Oak Ridge Associated Universities (ORAU), 2009



Recognized Professor, by the Honor Society of Phi Kappa Phi undergraduate and graduate students considering the one faculty member who made the most profound impact on their academic development, 2009



Royal E. Cabell Fellowship (Dissertation Year Fellowship), Northwestern University, 2005-2006



NSF Summer Institute on Nanoscale Mechanics, Bio-inspired Hierarchical Structures Fellowship Recipient, 2005



NSF Summer Institute on Multiscale Modeling of Nanomechanics and Materials Fellowship Recipient, 2004



Walter P. Murphy Fellowship, Northwestern University, 2001-2002

D. EDITOR/EDITORIAL REVIEW BORAD MEMBERSHIP FOR SCHOLARLY PUBLICATIONS Editorial Board Member, Guest Editor,

American Journal of Biomedical Engineering Journal of Nanomaterials

E. SCHOLARLY PRESENTATIONS E1. INVITED PRESENTATIONS 5

1. “Modeling of Local Inflammatory Factors Regulating Targeting Nanocarriers to Inflamed Endothelium” , Invited talk at 6th International Conference on Nanotechnology: Fundamentals and Applications, Barcelona, July 17, 2015 2. “Adhesion and Detachment of Circulating Tumor Cells” , Invited talk at World Congress of Biomechanics, Boston, July 6-11, 2014 3. “Characterization of Nanoparticle Targeted Delivery and Biodetection at Ultralow Concentration”, invited talk at Chongqing University, May 13, 2013 4. “Micropatterned Surface for Circulating Tumor Cell Capturing”, invited plenary talk at the Northeastern Bioengineering Conference, March 18, 2012 5. “Nanoparticle Targeted Delivery and Circulating Tumor Cell Capturing: Multiscale Characterization and Design”, invited talk at the University of Maryland at Baltimore County, Oct 14, 2011 6. “A Hybrid Particulate and Continuum Model of Nanoparticle-blood Cell Interaction”, invited talk at Society of Engineering Science Annual Technical Conference, Evanston, IL, Oct 12-14, 2011 7. “Characterization of the Effects of Particle Shape and Blood Cells on Nanoparticle Delivery Efficiency”, invited poster/flash talk, 2011 Multiscale Modeling (MSM) Consortium Meeting, Oct 5-6, 2011 8. “Nanotechnology and Nanomedicine in Translational Research”, invited talk at the Institute for Hepatitis and Virus Research, 15 June, 2011 9. “Nanoparticle Targeted Drug Delivery under Vascular Environment: Engineering Design, Simulation, and Applications”, invited talk at Dartmouth College, May, 2010 10. “Multiscale Modeling of Nanoparticle Targeted Drug Delivery in Blood Flow”, invited talk at The University of Texas Health Science Center, Houston, Texas, May 3, 2010 11. “Shape Effect in Nanomedicine”, invited talk at UT Southwestern Medical Center, Dallas, Texas, July, 2009 12. “Mechanics at Bio-nano interface”, invited talk at Tsinghua University, Beijing, China, July, 2009 13. “Fluid-structure Interaction in Biological Systems”, invited talk at Southern Methodist University, Texas, July, 2009 E2. REFEREED PRESENTATIONS/CONFERENCES 1. Y. Liu*, A Thomas, V. Muzykantov, D. Ou-Yang, L. Lowe-Krentz, “A Microfluidic Device for Characterization of Nanoparticle Delivery”, 4th ASME Micro/Nanoscale Heat & Mass Transfer International Conference, Hong Kong, Dec 12-15, 2013 2. Y. Liu*, A Thomas, “A Biomimetic Microfluidic Device for Characterization of Nanoparticle Delivery”, ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology (NEMB2013), Boston, MA, Feb 2-6, 2013 5

3. Y. Liu*, A Thomas, “Efficient Capturing of Circulating Tumor Cells in Microfluidic Devices”, ASME IMECE, Houston, TX, Nov 9-15, 2012 4. Y. Liu*, A Thomas, “Efficient Capturing of Circulating Tumor Cells in Microfluidic Devices”, ASME IMECE, Houston, TX, Nov 9-15, 2012 5. Y. Liu*, J. Tan, “A Mutiscale Particle-Cell Hybrid Model for Nanoparticle Delivery in Blood Flow”, ASME IMECE, Houston, TX, Nov 9-15, 2012 6. A Thomas, Y. Liu*, “Characterization of Nanoparticle Distribution in Microcirculation ”, ASME IMECE, Houston, TX, Nov 9-15, 2012 7. Y. Liu*, W. Hu, “Characterization of electrokinetic effect in biomolecule detection by nanosensors at ultralow concentration”, ACS Colloids and Surfaces, Baltimore, MD, June 11-13, 2012 8. Y. Liu*, A. Thomas, J. Tan, “Characterization of nanoparticle distribution in microcirculation: The influence of blood cells and vascular geometry”, ACS Colloids and Surfaces, Baltimore, MD, June 11-13, 2012 9. Y. Liu*, J. Tan, A. Thomas, “Multiscale Modeling of Nanoparticle Targeted Delivery in Vascular Environment”, NSF CBET Grantee Conference, Baltimore, MD, June 6-8, 2012 10. Y. Liu*, A. Thomas, X. Chen, “Efficient Capturing of Circulating Tumor Cells in Microfluidic Device”, 3rd ASME Micro/Nanoscale Heat & Mass Transfer International Conference, Atlanta, March 3-6, 2012 11. J. Tan, A. Thomas, Y. Liu*, “Influence of Red Blood Cells on Nanoparticle Targeted Delivery in Microcirculation”, American Physics Society Division of Fluid Dynamics Annual Meeting, Baltimore, MD, Nov 20-22, 2011 12. Y. Liu*, D. DePietro, A. Thomas, C. Chen, S. Yang “Surface Design for Efficient Capturing of Rare Cells in Microfluidic Device”, American Physics Society Division of Fluid Dynamics Annual Meeting, Baltimore, MD, Nov 20-22, 2011 13. J. Yang, M. Liang, Y. Liu, N. Huang, “Investigating Behaviors of Balloon Angioplasty for Heavily Calcified Lesions by Finite Element Method”, International Conference on Computational & Experimental Engineering and Sciences, ICCES1120110131467, April 18-20, 2011 14. Y. Liu*, J. Tan, A. Thomas “A Hybrid Particle-Cell Model for Nanoparticle Targeted Delivery in Microcirculation”, 2011 ASME Summer Bioengineering Conference, Farmington, PA, June 22-25, 2011 15. Y. Liu*, J. Tan, K. Ngyuen “A Hybrid Particulate And Continuum Model of Nanoparticle-blood Cell Interaction” (invited), 48th Annual Technical Meeting of Society of Engineering Science, Evanston, IL, Oct 12-14, 2011 16. Y. Liu*, Q. Guo, W. Hu “Modeling Electrokinetic Effect In Biomolecule Detection By Nanosensors”, 48th Annual Technical Meeting of Society of Engineering Science, Evanston, IL, Oct 12-14, 2011 17. Y. Liu*, A. Thomas, X. Cheng, S. Yang “Efficient Circulating Tumor Cell Capturing in Microfluidic Devices” (invited), Cancer Detection and Diagnostics Technologies for Global Health, NIH campus, Rockville, Maryland, August 22–23, 2011 18. Y. Liu*, J. Tan, A. Thomas “Characterization of the Effects of Particle Shape and Blood Cells on Nanoparticle Delivery Efficiency”, 2011 Multiscale Modeling (MSM) Consortium Meeting, NIH campus, Bethesda, Maryland, October 5-6, 2011 19. Y. Liu*, J. Tan, K. Ngyuen “Characterization of Nanoparticle Targeted Delivery in Microcirculation”, Biomedical Engineering Society Annual Meeting, Austin, TX, 2010 5

20. Y. Liu*, J. Tan, S. Shah, "A Hybrid Model for Nanoparticle Targeted Delivery in Blood Flow", 2010 First Global Congress on NanoEngineering for Medicine and Biology, Houston, TX, 2010 21. Y. Liu*, S. Shah, W. Hu, " Characterization of Biosensor Detection Process at Ultra-low Concentration Through a Stochastic Particle Model", 2010 First Global Congress on NanoEngineering for Medicine and Biology, Houston, TX, 2010 22. A. Ramachandran*, Q. Guo, S. Iqbal, Y. Liu, “Modeling DNA Translocation Kinetics in Nanopores with Selectivity”, 2010 First Global Congress on NanoEngineering for Medicine and Biology, Houston, TX, 2010 23. Y. Liu*, M. Mariyappa, S. Shah, J. Tan, K. Nguyen, “Modeling Targeted Drug Delivery in a Vascular Network”, 2010 First Global Congress on NanoEngineering for Medicine and Biology, Houston, TX, 2010 24. Y. Liu*, S. Shah, "Modeling Adhesion of Micro/Nanoparticles under Flow for Nanomedicine Application", 2009 Summer Bioengineering Conference, Lake Tahoe, CA, 2009 25. W. Miller*, B. Han, Y. Liu, “Tissue-Light Interaction During Monitoring Of Thermal Lesion Using Quantum Dot Mediated Fluorescence Thermometry”, 2009 Summer Bioengineering Conference, Lake Tahoe, CA, 2009 26. Y. Liu, A. Ramachandran*, S. Iqbal, “The Effects of Bio-functionalization on Solid-state Nanopore Transport”, American Physical Society March Meeting, Pittsburgh, PA, 2009 27. A. Ramachandran*, Y. Liu, S. Iqbal, “DNA Translocation in Functionalized Nanopores”, graduate Dean's poster award, ACES symposium 2009 28. Y. Liu*, S. Shah, W. Hu, J. Gao, “Modeling Particle Shape-Dependent Dynamics in Nanomedicine”, Proceedings of First Annual ORNL Biomedical Science and Engineering Conference, Oak Ridge, 2009 29. Y. Liu*, S. Shah, W. Hu, J. Gao, “Adhesion Dynamics of Functional Nanoparticles for Targeted Drug Delivery”, Proceedings of the 25th Southern Biomedical Engineering Conference, Miami, 2009 30. J. Yang*, M.B. Liang, N. Huang, S. Shah, Y. Liu, “Studying the Non-uniform Expansion of a Stent Influenced by the Balloon”, Proceedings of the 25th Southern Biomedical Engineering Conference, Miami, 2009 31. Y. Liu*, S. Iqbal, “A Mesoscale Model for Molecular Interaction in Functionalized Nanopores”, ASME 2008 International Mechanical Engineering Congress (Proceedings of IMECE 2008), IMECE2008-68542, 2008 32. S. Shah*, Y. Liu, W. Hu, J. Gao “Modeling Nanoparticle Transportation and Adhesion in Nanomedicine”, ASME 2008 International Mechanical Engineering Congress (Proceedings of IMECE 2008), (Poster) 33. A. Ramachandran*, Y. Liu, S. Iqbal, “Characterization of DNA-Nanopore interaction and translocation”, Biotechnology and Bioinformatics Symposium, 2008 (Poster) 34. Y. Liu*, J. Chung and K. Lee, “Size Selective Capturing of Biomolecules and Nanoparticles by Combined Dielectrophoresis and Surface Tension”, 8th World Congress on Computational Mechanics, Venezia, Italy, 2008 35. Y. Liu*,“Fluid Structure Interaction for Biomechanical Applications”, Mechanical & Aerospace Engineering Seminar, UTA, 2008 36. W.H. Yeo*, J.H. Chung, Y. Liu, K. H. Lee, Direct concentration of circulating DNA by using a nanostructured tip, Proceedings of SPIE NanoScience+Engineering, San Diego, 2008. 5

37. W.H. Yeo*, J.H. Chung, Y. Liu, K. H. Lee, Direct Concentration of Circulating DNA by Using a Nanostructured Tip, Proceedings of UKC2008, San Diego, 2008

38. W. Yeo*, J. Chung, K. Lee, Y. Liu, and W.K. Liu, “Hybrid fiber Fabrication Using an AC Electric Field and Capillary Action”, Proceedings of IMECE’07, 2007 39. Y. Liu*, J. Chung, W.K. Liu, “Electrokinetic Assembly and Manipulation of Bio-nanomaterials”, Ninth U.S. National Congress on Computational Mechanics, San Francisco, California, 2007 40. Y. Liu*, S. Lichter, W.K. Liu, A. Roxin, “Slip Dynamics at the Liquid/Solid Interface in MD Simulations”, 2005 American Physical Society Division of Fluid Dynamics 58th Annual Meeting, Chicago, IL 41. A. Roxin, Y. Liu, S. Lichter*, W.K. Liu, “Slip at the Liquid/Solid Interface: A Dynamical Theory”, 2005 American Physical Society Division of Fluid Dynamics 58th Annual Meeting, Chicago, IL 42. Y. Liu*, J. Chung, W.K. Liu, N. Patankar, and R. Ruoff, “Modeling Electric Field Guided Assembly of Nano/bio-filaments”, Eighth U.S. National Congress on Computational Mechanics, Austin, Texas, 2005 43. Y. Liu*, W.K. Liu, N. Patankar, and J. Chung, “Electrohydrodynamics of Immersed Continua”, Eighth U.S. National Congress on Computational Mechanics, Austin, Texas, 2005 44. Y. Liu*, L. Zhang, W. Liu, “Studies on Red Blood Cell Aggregations using Immersed Finite Element Method”, Seventh U.S. Congress Conference of Computational Mechanics, New Mexico, 2003 45. Y. Liu*, W.K. Liu, L. Zhang, R. Ruoff, “Nanotube Fluidics”, Proceedings of 2002 ASME International Mechanical Engineering Congress & Exposition, New Orleans, Louisiana, 2002 46. L. Zhang*, W.K. Liu and Y. Liu, “Molecular Flow Past a Single-Walled Carbon Nanotube”, Conference paper of Fifth World Congress on Computational Mechanics 2002, Vienna, Austria 47. G. Wagner*, W.K. Liu, Y. Liu, L. Zhang, R. Ruoff, “Coupling of Molecular Dynamics with Continuum Mechanics via a Bridging Scale Approach”, Proceedings of 2002 ASME International Mechanical Engineering Congress & Exposition, New Orleans, Louisiana E3. CHAIRED SESSIONS/CONFERENCES • Chair of “Novel Device and Modeling for Particle and Cell Transport” session, 2014 World Congress of Biomechanics, Boston, July, 2014 • Chair of “Micro- and Nano-Fluidic Platforms for Evaluation of NanoBioMaterials” session, 2013 ASME NEMB Conference • Topic co-organizer of “Transport Phenomena in Biomedical Applications”, 2012 ASME IMECE Conference • Chair of “Microfluidics: General V” session, 2011 APS DFD conference • Chair of “Mesh-Reduction and Mesh-Based Multiscale Computational Methods” session, 2011 Society of Engineering Science (SES) annual technical conference • Chair of “Immersed Method for Fluid Structure Interaction” session, 2011 SES conference • Chair of “Mutiscale Modeling in Biotansport”, 2011 ASME Summer Bioengineering conference 5

• Chair of “Bionanotechnology in Diagnosis and Treatment” session, 2010 ASME Summer Bioengineering conference • Organizer of "12-26 Synergy, Complexity and Self-Organization in Engineered Material Systems" Minisymposia in 2010 ASME IMECE, Vancouver, 2010 • Organizer of "Multiphysics Multiscale Enabling Materials I - Nano- and Biosystems" session, COUPLED PROBLEMS, Italy, 2009 • Chair of “Multiscale Methods and Applications to Nano- and Bio- Mechanics and Materials” session, Ninth U.S. National Congress on Computational Mechanics, 2007 F. PROFESSIONAL SERVICE F.1. Office and Committee Memberships Held in Professional Organizations ASME Technical Committee on Mechanics in Biology and Medicine Biotransport committee, ASME Summer Bioengineering Conference ASME NanoEngineering Council

2011-Present 2010-Present 2013-Present

F.2. Panelist and Reviewer for Federal Agencies NSF Panel Review, division of CBET NIH R15 Grant Review NIH CSR Grant Review NSF International Collaboration Grant Review NSF Panel Review, division of CBET, CMMI NSF IDR Panel Review NIH Challenge Grant Review

2014 2013 2013 2012 2008, 2009, 2010, 2011 2010 2009

F.3. Peer Review Services Journals:

Computational Mechanics Computer Methods in Applied Mechanics and Engineering Journal of Biomechanics Journal of Physical Chemistry B Journal of Fluids Engineering Journal of Biorheology Annals of Biomedical Engineering Journal of Computational Physics Biomechanics and Modeling in Mechanobiology International Journal of Numerical Methods and Engineering Soft Matter Lab on Chip ACS Nano Journal of Nanotechnology in Engineering and Medicine Microfluidics and Nanofluidics Scientific Report

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