A New Algorithm for the Quantitation of Myocardial Perfusion SPECT
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A New Algorithm for the Quantitation of Myocardial Perfusion SPECT
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A New Algorithm for the Quantitation of Myocardial Perfusion SPECT. II: Validation and Diagnostic Yield Tali Sharir, Guido Germano, Parker B. Waechter, Paul B. Kavanagh, Joseph S. Areeda, Jim Gerlach, Xingping Kang, Howard C. Lewin, and Daniel S. Berman Departments ofimaging
and Medicine and Burns andAllen Research Institute, Cedars-Sinai Medical Center@Los Angeles, California
This study validates a new quantitative perfusion SPECT algo rithmforthe assessmentof myocardialperfusion.The algorithm is not based on slices and providesfully 3-dimensionalsampling and analysis independent of assumptions about the geometric shape of the left ventricle. Methods: Radiopharmaceutical- and sex-specificnormallimitsandthresholdsforperfusionabnormal ity in 20 segments of the left ventricle were developed for separate, dual-isotope rest@°1Tl—exercise @“Tc-sestamibi SPECT in 36 patients with
