Additional file 2

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1.78 1.32-2.41. Charlson Comorbidity Index. Median (25% perc./75% perc./range). 1 (1/2/12). 1 (1/1/9). NA NA. Charlson Comorbidity Index (categories). 0.
Additional file 2 Flowchart study population:

Detailed information on characteristics and co-medication of cases and controls for each outcome at the index date: Characteristics and co-medication of cases with bone-related conditions and matched controls at the index date No. of Cases (%) No. of Controls (%) Crude OR 95% CI (N=8,907) (N=35,445) Male 2,752 (30.9) 10,956 (30.9) NA NA 6,155 (69.1) 24,489 (69.1) NA NA Female Age 18-39 2,321 (26.1) 9,263 (26.1) NA NA 40-59 2,713 (30.5) 10,858 (30.6) NA NA 60-79 2,947 (33.1) 11,781 (33.2) NA NA ≥80 926 (10.4) 3,543 (10.0) NA NA Smoking status non 4,495 (50.5) 18,672 (52.7) 1.00 reference current 1,438 (16.1) 5,020 (14.2) 1.20 1.12-1.29 ex 2,767 (31.1) 10,935 (30.9) 1.05 0.99-1.10 unknown 207 (2.3) 818 (2.3) 1.06 0.90-1.25 Alcohol consumption (average units per week) none 4,231 (47.5) 16,714 (47.2) 1.00 reference