Sep 15, 2016 - quently (6 vs 3%, p=0.002), as well as angina recurrence (8 vs 5%, p=0.045), heart failure (12 ..... vasospastic angina (STELLA trial). J.H. Kim1 ...
Rapid Fire – Understanding the diversity of acute coronary syndromes
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3513 | BEDSIDE Invasive strategy and outcomes: gender differences in patients with non st-elevation acute coronary syndrome during coronary care unit hospitalisation. an Italian national survey (BLITZ-3) T.C. Aranzulla 1 , M.R. Conte 1 , L. Gonzini 2 , G. Casella 3 , M. Cassin 4 , A. Chinaglia 5 , G. Fradella 6 , S. Pirelli 7 , G. Scorcu 8 , L. Oltrona Visconti 9 on behalf of BLITZ 3 Investigators. 1 Mauriziano Hospital, Department of Cardiology, Turin, Italy; 2 ANMCO Research Center, Florence, Italy; 3 Maggiore Hospital, Department of Cardiology, Bologna, Italy; 4 Santa Maria degli Angeli Hospital, Department of Cardiology, Pordenone, Italy; 5 Maria Vittoria Hospital, Department of Cardiology, Turin, Italy; 6 Cardiology Department 1, AOU Careggi, Florence, Italy; 7 Cardiology Department, Istituti Ospitalieri, Cremona, Italy; 8 G. Brotzu Hospital, Department of Cardiology, Cagliari, Italy; 9 Cardiology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
3514 | SPOTLIGHT 2013 The risk of ischemic stroke after an acute myocardial infarction in diabetic subjects S. Jakobsson 1 , L. Bergstrom 2 , F. Bjorklund 3 , T. Jernberg 4 , T. Mooe 1 . 1 Umea University, Department of Public Health and Clinical Medicine, Umea, Sweden; 2 Department of Medicine, Section of Neurology, Ostersund Hospital, Ostersund, Sweden; 3 Department of Medicine, Section of Cardiology, Ostersund Hospital, Ostersund, Sweden; 4 Karolinska Institute, Department of Medicine, Cardiology Unit, Stockholm, Sweden Purpose: The incidence, any trend over time and predictors of ischemic stroke after an Acute Myocardial Infarction (AMI) in patients with diabetes mellitus are unknown. Methods: Data for 173233 unselected AMI patients, including 33503 diabetic subjects, was taken from the Swedish Register of Information and Knowledge about Swedish Heart Intensive Care Admissions (RIKS-HIA) registry during 1998-2008. Ischemic stroke events were recorded during one year of follow-up. Results: Diabetic subjects more often had a history of cardiovascular disease, received less reperfusion therapy and were treated with Acetylsalicylic Acid (ASA), P2Y12-inhibitors and statins to a lesser extent than nondiabetic subjects. However, the use of evidence based therapies increased markedly in both groups during the study period. The incidence of ischemic stroke during the first year after the AMI decreased from 7.1 to 4.7% and from 4.2 to 3.7% in diabetic and nondiabetic subjects, respectively. The risk reduction was significantly larger in the diabetic subgroup. Reperfusion therapy, ASA, P2Y12-inhibitors and statins were independently associated with the reduced stroke risk. Conclusion: Ischemic stroke is not an uncommon complication after an AMI in diabetic subjects but the risk of stroke has markedly decreased during recent years. The increased use of evidence based therapies importantly contributes
Figure 1. Hazard ratios of ischemic stroke in nondiabetic patients during the study period. DM, diabetes mellitus, HR, hazard ratio.
to this risk reduction, particularly in diabetic subjects, but there is still room for improvement.
3515 | BEDSIDE Postprocedural TIMI flow grade 2 in patients with non-ST-segment elevation myocardial infarction undergoing percutaneous coronary revascularization. (PL-ACS Registry) J. Karwowski 1 , M. Gasior 2 , I. Kowalik 1 , M. Gierlotka 2 , L. Polonski 2 , H. Szwed 1 . 1 Institute of Cardiology, 2nd Department of Coronary Artery Disease, Warsaw, Poland; 2 Medical University of Silesia, Silesian Center for Heart Diseases, 3rd Department of Cardiology, Zabrze, Poland Purpose: The purpose of this study was to evaluate the clinical impact of postprocedural TIMI flow in an infarct-related artery (IRA) on outcomes in patients with non-ST-segment elevation myocardial infarction undergoing percutaneous coronary revascularization. Methods: A total of 2767 patients with NSTEMI enrolled in the Polish Registry of Acute Coronary Syndromes (PL-ACS) who underwent an invasive strategy with percutaneous coronary intervention (PCI) were analyzed. Patients were divided in 3 groups according to postprocedural culprit vessel TIMI flow (TIMI 0/1: 90 patients - 3,26%, TIMI 2: 61 patients - 2,20%, TIMI 3: 2616 patients - 94,54%). Results: The in-hospital mortality for the TIMI 0/1, TIMI 2 and TIMI 3 was adequately 12,22% vs 13,11% vs 3,44% (p
