Association of long-term blood pressure variability and brachial-ankle

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received: 28 August 2015 accepted: 21 January 2016 Published: 19 February 2016

Association of long-term blood pressure variability and brachialankle pulse wave velocity: a retrospective study from the APAC cohort Yang Wang1,*, Yuling Yang1,*, Anxin Wang2,3,4,5,6,*, Shasha An1, Zhifang Li1, Wenyan Zhang1, Xuemei Liu1, Chunyu Ruan1, Xiaoxue Liu7, Xiuhua Guo6, Xingquan Zhao2,3,4,5 & Shouling Wu8 We investigated associations between long-term blood pressure variability (BPV) and brachial-ankle pulse wave velocity (baPWV). Within the Asymptomatic Polyvascular Abnormalities Community (APAC) study, we retrospectively collected long-term BPV and baPWV measures. Long-term BPV was calculated using the mean and standard deviation of systolic blood pressure (SBP) across 4 years based on annual values of SBP. In total, 3,994 subjects (2,284 men) were eligible for inclusion in this study. We stratified the study population into four SBP quartiles. Left and right baPWV was higher in participants with long-term SBPV in the fourth quartile compared with the first quartile (left: 1,725 ± 488 vs. 1,461 ± 340 [p