Clinical diagnostic indices of obese patients

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May 22, 2016 - INTRODUCTION. Obesity is a disease condition in which excess body fat ... syndrome, Cohen syndrome, and MOMO syndrome, among others ...
In tern a tio n a l Sch o la rs Jo u rn a ls International Journal of Medicine and Medical Sciences ISSN: 2167-0404 Vol. 6 (5), pp. 332-339, May, 2016. Available online at www.internationalscholarsjournals.org © International Scholars Journals Author(s) retain the copyright of this article.

Full Length Research Paper

Clinical diagnostic indices of obese patients *1

Obimba, Kelechukwu Clarence, 2Ozougwu, Jevas Chibuike, 3Emejulu Ada A, and 4 Ihedimbu, Perpetua Chiamaka

*1,3.4 2

Department of Biochemistry, School of Biological Sciences, Federal University of Technology Owerri. Nigeria. Physiology and Biomedical Research Unit, Department of Biological Sciences, Rhema University, Aba, Abia State, Nigeria. Received 22 April, 2016; Accepted 13 May, 2016; Published 22 May, 2016

The aim of the study was to investigate the efficacy of the use of biochemical, hematological, blood pressure and anthropometric indices as diagnostic parameters of obesity. The experimental design was a single factor completely randomized design (CRD). Twenty (20) normal human subjects and thirty (30) obese patients were subjected to systolic (SP) and diastolic (DP) blood pressure, body mass index (BMI), serum glycated albumin (GA), fasting blood sugar (FBS), serum aspartate aminotransferase (AST), serum glycated hemoglobin (HbA1c), serum leptin (L), serum total cholesterol (C) and serum triglyceride (T) tests. Results recorded of the normal human subjects and obese patients, expressed as mean ± standard error (S.E) (unit) were as follows : SP (120.52 ± 9.14) and (146.87 ± 11.23) (mmHg), DP (75.6±1.7) and (90.11±0.9) 2 (mmHg), BMI (15.3±0.7) and (30.5 ±1.7) (kg/m ), GA (15.5±0.2) and (13.1±0.3) (%), FBS (68.8±4.7) and (125.8±1.7) (mg/dl), AST (9.2 ±1.9) and (22.5 ±1.0) (U/l), HbA1c (6.15 ±0.4) and (8.15 ±0.3) (%), L (10.5 ±1.0) and (31.5 ±1.0) (ng/ml.kg), C (170±1.5) and (195±2.0) (mg/dl), and T (175.51±2.3) and (110.2±0.215) (mg/dl), respectively. The mean values of SP, DP, and BMI, FBS, AST, HbA1c, L, C and T were significantly higher (p