Conference Program

The Engine of Growth for a Better Life

22.2.2018 nom .D'DlMipn

T31D

i

Conference Program

12:30

Advanced Biomaterials for Regenerating Diseased Organs Tal Dvir Sagol Center for Regenerative Biotechnology, Laboratory fo and Regenerative Medicine, School of Molecular Cell Biolog Department of Materials Science and Engineering, The Cente Nanotechnology, Tel Aviv University, Israel

12:45

2.SD Printing of Drug-Delivery Microspheres from Melt Tal Shpigel, Almog Uziel, Dan Lewitus Polymers and Plastics Engineering, Shenkar-Engineering. De

12:50

Post Marketing Trial Results of Total Hip Replacement Using MP-1 ™ Alisa Buchman', SImha Sibony', James P. Burn^ 'MMATECH Ltd Israel ^Orthopedics, FRACS, New Zealand

12:00-13:00

Session 9: Cardiovascular I

Rimon Hall

Chairpersons: Amir Landesberg, Netanel Korin 12:00

Transgene Independent Generation of Functional SinoAtrial Node-Like Pacemaker Cells from hPSCs Udi Nussinovitch Department of Cardiology, Meir Medical Center, Israel

12:15

Heart-on-Chip Devices for Scientific Discoveries and Pharmacological Screening Moran Yadid, Kevin Kit Parker Disease Biophysics Group, Harvard SEAS, USA

12:30

CorAssist Cardiovascular CORolla' Device for Treatment of Heart Failure with Preserved Ejection Fraction (HFpEF) YotamReisner.YairFeld Corassist, Cardiovascular Ltd., Israel

12:45

The Vicious Cycle of Dyspnea in Patients with Heart Failure Anna Faingersh-Klebanov', Shmuel Rispler^ Eugenia Nikolsky^ Yuval Cohen^ Arthur Kerner^ Sergey Yalonetsky^ Amnon Eitan^ Ariel Roguin^ Amir Landesberg' ^Faculty of Biomedical Engineering, Technion-lsrael Insti Cardiology Rambam Health Care Campus, Israel

12:00-13:00

12:00

Session 10: Systems and Synthetic Biology Chairpersons: Tamir Tuller, Johann Elbaz

Hadas Hall

Learning Therapeutic Automata Ido Bachelet

12:15

Leveraging the 3D Genome to Solve Genome Assembly Noam Kaplan Department of Physiology, Biophysics & Systems Biology, R Medicine, Technion Israel Institute of Technology, Israel

ISMBE Biomedical Engineering 2018

113

1

Investigation of Ultrasound Properties of the Brain Under Different Thermal Conditions Dahis Daniel, Haim Azhari

Biomedical Engineering, Technion Institute of Technology, I 2

Post Marketing Trial Results of Total Hip Replacement Using MP-I" Alisa Buchman', Simha Sibony', James P. Burn^

'MMATECH Ltd Israel •'Orthopedics, FRACS, New Zealand 3

Enhanced Hydrogen Photo-Production in Microalgae by Computational based Genetic Engineering IddoWeiner'^, IftachYacobyMamir Tuller'

^Department of Biomedical Engineering, The Iby and Aladar Fle Aviv University, The Lab for Computational, Systems and Synth ^School of Plant Sciences and Food Security, The George S. Wise University, The Lob for Renewable Energy Studies, Israel 4

The Use of Skeletal Muscle-Derived Pericytes in Tissue Engineering of Skeletal Muscle Graft based on 3D Pluronic-Fibrinogen (FF-127) Hydrogel Environment Raziel Hamami, Dror Seliktar

Bio Medical Engineering, Thechnion, Israel 5

Experimental Study of Methods for Treatment of Aortic Arch Aneurysm Shirly S t e i n l a u f A l e x Liberzon', Idit Avrahami^

^Mechanical engineering, Tel Aviv University Israel ^Mechanical Engineering & Mechatronics, Ariel University, Is 6

Novel Optical Sensor in Toilet Aimed at Extracting Vital Medical Information from Excretions Yaara Kapp-Barnea

OutSense, Israel 7

Calibration-Free Pulse Oximetry Based on Two Wavelengths in the Infrared Ohad Yossef Hay'\r Cohen', Itamar Nitzan^ Ruben Bromiker^ Yair Kasirer^ Yitzhak Yitzhaky', Meir Nitzan', Shiomo Engelberg'

^Department of Physics/Electro-Optics Engineering, Jerusalem 'Neonatal Intensive Care Unit, Shaare Zedek Medical Center, ^Department of Electro-Optics Engineering, Ben-Gurion Univer 8

Characterization of Normal and Blepharospasm Blinks by the Eyelid Motion Monitor Adi Hanuka', Oz Levinkron^ Shir Laufer', Naama Pearl', Daniel Briscoe^ Levi Schachter'

^Electrical Engineering, Technion, Israel 'Faculty of Medicine, Technion, Israel

20

I February 22"", 2018

Session 8: Novel Biomaterials Post Marketing Trial Results of Total Hip Replacement Using MP-I™ Alisa Buchman', Simha Sibony', James P. Burn^

'MMATECH Ltd, Israel, 'Orthopedics, FRACS, New Zealand The need for a more durable, metal free, non-osteolytic particle generating material in Total Hip Replacement (THR) is urgently required to reduce revision surgeries. Current used materials; Ceramic, metal and UHMWPE remain discrepant for long-term use. Polyimide (MP-1™) is a high performance biopolymer, originating from aerospace industry. MP-l™ exhibits a self-lubrication property required for bearings and articulating joints. Being resistant to fatigue, creep and chemicals and sterilisable by autoclave or irradiation, MP-1 ™ is ideal for medical devices. Finalizing pre-clinical testing, t w o patients were implanted 12 years ago after informed consent. The Ethical Committee approved 100 patients in a single surgeon (PJB) post-marketing trial running Delta ceramic femoral ball against MP-1liner. Age range is from 81 to 43 years. The younger patients now being offered MP-l'", in view of the retrieval data. Out of the 74 enrolled patients, 44 patients have the implant for more than 5 years. The only "Complications" in a few patients was an initial squeak which spontaneously disappears by 10 days and never returns. There have been no dislocations or restrictions on activity level. Oxford and Harris Hip scores along with radiology, blood and clinical examination showed remarkable results during follow-up. MP

biomaterial is used for other medical devices as well such as dental implants and trauma nails

and screws.

ISMBE Biomedical Engineering 2018 |

55