Correction: Integration of flux measurements to resolve changes in ...
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Biochem. J. 2017, volume 474, issue 16, pages, 2785–2801; https://doi.org/10.1042/BCJ20170474 In the isotopologue analysis of glycero( phospho)lipids (Figure 5), the authors mistakenly included glycerolipids with only the glycerol moiety labeled (i.e., m+3) in the Glycerol + Fatty Acid labeling groups (Glycl+FA). Fractional enrichment of 13C into Glycl+FA of panels B−F should include only those glycerolipids having both the glycerol and fatty acyl chains labeled (e.g. this would include m+5, m+7, m+9, m+11, m+13, m+15, etc.). The corrected figure is presented here. These changes do not change the conclusions drawn from the study and do not require modifications to the text of the manuscript.
Figure 5. Phosphofructokinase regulates glycerolipid biosynthesis. Stable isotope tracing of phospholipids and triacylglycerols in cardiomyocytes incubated with media containing 13C6-glucose for 18 h: (A) atom-resolved map illustrating the biological and biochemical history of 13C incorporation into glycerolipids; fractional enrichment values of 13C into: (B) PC; (C) PI; (D) PE; (E) PS; and (F) TAG. Graph represents three replicates per group from one isolation. *,$P < 0.05, **,$$P < 0.01, ****P < 0.0001.
