Correlation of Age-Related Metabonomic Changes in ... - Bentham Open
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Open Access
Correlation of Age-Related Metabonomic Changes in 1H NMR Serum and Urine Profiles of Rats with Cognitive Function Abbas Ali Mahdi*,1, Sanjay Annarao2, Sandeep Tripathi1, Akbar Nawab1, Farzana Mahdi3, Mahdi Hasan4, Raja Roy2 and C.L. Khetrapal2 1
Departments of Biochemistry, King Georges’ Medical University, Lucknow-226003; 2Centre of Biomedical Magnetic Resonance, Sanjay Gandhi Post Graduate Institute of Medical Sciences Campus, Raebareli Road, Lucknow-226014; 3 Department of Biochemistry, Era’s Lucknow Medical College and Hospital, Lucknow, Uttar Pradesh, India; 4Anatomy, King George’s Medical University, Lucknow-226003, India Abstract: Age related metabonomic changes in young and aged male albino rats have been investigated using Proton Nuclear Magnetic Resonance (1H NMR) spectroscopy. The studies were performed using ‘in vivo’ behavioral and metabonomic assessment in serum and urine of the rats. Significant changes (p
