Effect of dietary bovine lactoferrin on performance and ...

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vitamin E, ascorbic acid, ß-carotene, glutathione and metal chelators such as lactofer- .... 20 mg; D-pantothenic acid 12.00 mg; biotin 0.08 mg; folic acid 0.30 mg; ...
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Animal Feed Science and Technology 140 (2008) 326–336

Effect of dietary bovine lactoferrin on performance and antioxidant status of piglets夽 Y.Z. Wang ∗ , C.L. Xu, Z.H. An, J.X. Liu, J. Feng Key Laboratory of Molecular Animal Nutrition of Ministry of Education, Feed Science Institute, Zhejiang University, Hangzhou 310029, PR China Received 4 September 2006; received in revised form 21 January 2007; accepted 14 February 2007

Abstract The experiment investigated the effect of dietary bovine lactoferrin (bLF) on growth performance and antioxidant systems of piglets. Duroc–Landrace–Yorkshire crossbred female piglets (n = 120, 35 days of age, live-weight 9.70 ± 0.71 kg) were fed a diet containing 0, 1250 or 2500 mg/kg bLF for 30 days. After completion of the feeding experiment, eight animals from each treatment were randomly selected to determine malondialdehyde (MDA) and total antioxidant capacity (TAOC), copper–zinc–superoxide dismutase (CuZnSOD), glutathione peroxidase (GPx), catalase (CAT) activities in serum and longissimus muscle, and CuZnSOD, GPx and CAT mRNA levels in longissimus muscle. Results showed that supplementation with bLF improved average daily gain (ADG), average daily feed intake (ADFI) and reduced diarrhea ratios of piglets with the linear and quadratic polynomial contrasts being significant (P