Effect of hypothermia on brain tissue oxygenation in patients with severe head injury. A. K. Gupta1,2*, P. G. Al-Rawi3, P. J. Hutchinson3 and P. J. Kirkpatrick3.
British Journal of Anaesthesia 88 (2): 188±92 (2002)
Effect of hypothermia on brain tissue oxygenation in patients with severe head injury A. K. Gupta1,2*, P. G. Al-Rawi3, P. J. Hutchinson3 and P. J. Kirkpatrick3 Departments of 1Anaesthesia, 2Neuro Critical Care and 3Neurosurgery, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 2QQ UK *Corresponding author Background. There is renewed interest in the use of induced hypothermia as a method of neuroprotection both intraoperatively and in the intensive care management of severe brain injury. In this study we have investigated the effects of hypothermia on brain tissue oxygenation in patients with severe head injury. Methods. Thirty patients with severe head injury (Glasgow coma score