The Spectrum of Neuro-AIDS Disorders Pathophysiology, Diagnosis, and Treatment
Edited by
Karl Goodkin. M.D.. Ph.D.• FAPA Department of Psychiatry and Behavioral Neurosciences, Cedars-Sinai Medical Center, and Department of Psychiatry and Biobehavioral Sciences, University of California-Los Angeles, Los Angeles, California
Paul Shapshak. Ph.D. Ann Lowerey Murphey Laboratory, Department of Psychiatry and Behavioral Medicine, University of South Florida College of Medicine, Tampa, Florida
Ashok Verma. M.D.• D.M. Department of Neurology, University of Miami Miller School of Medicine, Miami, Florida
II ASM
PRESS
Washington, DC
Copyright © 2009
ASM Press American Society for Microbiology 1752 N Street, NW. Washington, DC 20036-2904
Library of Congress Cataloging-in-Publication Data The spectrum of neuro-AIDS disorders; pathophysiology, diagnosis, and treatment / edited by Karl Goodkin, Paul Shapshak, Ashok Verma. p. ;cm.
Includes bibliographical references and index.
ISBN 978-1-55581-369-7
1. Brain-Infections. 2. AIDS (Disease) 1. Goodkin, Karl. II. Shapshak, Paul. III. Verma, Ashok. [DNLM: 1. HIV Infections-eomplications. 2. AIDS-Related Opportunistic Infections. 3. Antiretroviral Therapy, Highly Active-adverse effects. 4. Central Nervous System Diseases-etiology. 5. Diagnostic Techniques, Neurological. 6. Mental Disorders-etiology. WC 503.5 S741 2009] RC359.5.S64 2009 616.97'92-dc22 2008039156 ISBN 1-978-1-55581-369-7
AU Rights Reserved Printed in the United States of America
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Contents
8. Neurologic Outcomes in HIV
Infection: Clinical Events and Surrogate
Markers / 95
Contributors / ix Preface / xiii
SECTION 1
_
DISORDERS DUE TO PRIMARY HIV-1 PATHOGENESIS AND THEIR TREATMENT / 1
CONSTANTIN T. YIANNOUTSOS
19)
Designing HIV gp120 Peptide Vaccines: '-Kt
