optimization to carry out an efficient search of large regions of inductive bias space. Experimental re- sults are reported demonstrating the system's capaci-.
SSO/B : Single Sign On with Blockchain. CMS/V : Content Management System with Value. POS : Point of Sales. O2O : Online
previously described [Rodriguez-Suarez et al., 2011]. Briefly, .... Anthony, 2011], which can be run on high content instruments such as the ... Berger, S.L., Kouzarides, T., Shiekhattar, R., and Shilatifard, A. (2009): An operational definition of.
Feb 18, 2010 - surface excess for gas adsorption on a graphite surface. D.D. Do ... popularity (mainly due to its simplicity) the BET method has received .... 1972; Gregg and Sing, 1985; Arnell and Henneberry, 1948; Chung ..... To get the total.
Direct mail is a typical example for response modeling to be used. In order to decide which ... randomly chosen people, as mass marketing does. A key characteristic of ... are left out of the mailing. As a consequence, costs are made that can be.
Feb 3, 2015 - Hong Zhan Wang1, Barbara Rosati1,2, Chris Gordon1, Virginijus Valiunas1,2, David McKinnon2,3,. Ira S. Cohen1,2 and Peter R. Brink1,2*.
Mar 10, 2017 - Apoptosis, also known as type I programmed cell death, is a selective ..... Khan, I., Guru, S. K., Rath, S. K., Chinthakindi, P. K., Singh, B., Koul,.
Figure S1. JQ1 decreases cell viability of both TNBC and ER+ breast cancer cell lines. TNBC. (MDA-MB-231, BT549) and ER+ (T47D, MCF7) breast cancer cell ...
Induction of USP17 by combining BET and HDAC inhibitors in breast cancer cells Supplementary Material
Figure S1. JQ1 decreases cell viability of both TNBC and ER+ breast cancer cell lines. TNBC (MDA-MB-231, BT549) and ER+ (T47D, MCF7) breast cancer cell lines were treated with the indicated concentrations of JQ1 for 48 hours. Changes in cell viability were assayed by trypan blue exclusion assay. Data are presented as mean (n=3) percentage +/- standard deviation (SD) relative to control.
A C e ll v ia b ilit y [ % ]
120 M D A -M B -2 3 1
100
BT549
80
T47D
60
M CF7
40 20 0 -5
-4
-3 -2 lo g 1 0 V P A [ M ]
-1
0
B
C
Figure S2. VPA reduces cell viability which is further potentiated by JQ1 treatment. (A) MDAMB-231, BT549, T47D and MCF7 cells were treated with increasing concentrations of VPA for 48 hours and assayed by WST-1 cell viability assay. (B) IC50 values were calculated by GraphPad Prism software. (C) Cells were treated with JQ1 (1 M) and VPA (8 mM for MDA-MB-231, 9 mM for BT549, 4 mM for T47D, 21.4 mM for MCF7) for 48 hours then assayed by WST-1 cell viability assay. Error bars represent SD from n ≥ 3 independent experiments. Significance (P value) of results in A and C was calculated using a two tailed t test (* P
