classified into three subtypes: 1) behavioral variant (bvFTD) ... Instrumental activities of daily living in clinical subtypes of ... Behavior Observer Checklist (SBOC),.
Instrumental activities of daily living in clinical subtypes of frontotemporal dementia Negar Moheb1, Mario F. Mendez1,2,3, Sarah A. Kremen1, and Edmond Teng1,3 Departments of 1Neurology and 2Psychiatry & Behavioral Sciences, David Geffen School of Medicine at UCLA; 3Neurobehavior Service, Veterans Affairs Greater Los Angeles Healthcare System Introduction • Frontotemporal dementia (FTD) has been classified into three subtypes: 1) behavioral variant (bvFTD), 2) semantic variant primary progressive aphasia (svPPA), and 3) non-fluent/agrammatic variant primary progressive aphasia (nfvPPA).
Figure 1: Total FAQ scores- A) overall and B) stratified by disease duration.
bvFTD N=264
• Prior work suggests that greater functional deficits are seen in bvFTD than in nfvPPA or svPPA1-4. • However, it remains uncertain if these FTD subtypes exhibit different patterns and/or predictors of functional decline.
Methods • We identified 894 FTD patients from the National Alzheimer Coordinating Center (NACC) Uniform Dataset (UDS), comprising three groups: bvFTD (n=607), svPPA (n=132), and nfvPPA (n=155). • Instrumental activities of daily living (IADLs) were assessed with the Functional Activities Questionnaire (FAQ).
Table 2: Predictors of total FAQ scorescognitive and behavioral
