Crohn's Disease â osteoporosis â colecalciferol â calcium. â ibandronate ... The high prevalence of osteoporosis related vertebral fractures in CD .... free period.
Intravenous Ibandronate or Sodium-Fluoride - a 3.5 Years Study on Bone Density and Fractures in Crohn’s Disease Patients with Osteoporosis Jochen Klaus1, Max Reinshagen2, Katharina Herdt1, Guido Adler1, Georg BT von Boyen1, Christian von Tirpitz3 1) University of Ulm, Department of Internal Medicine I, Ulm; 2) Städtisches Klinikum Braunschweig, Department of Internal Medicine I, Braunschweig; 3) Medizinische Klinik, Kreisklinik Biberach, Biberach, Germany
Abstract Background and Aim: Osteoporosis commonly afflicts Crohn’s disease (CD) patients. Management remains unclear, with limited results for intravenous (i.v.) bisphosphonates and a follow-up longer than one year. Intravenous bisphosphonates bypass gastrointestinal-tract irritation offering an interesting alternative suitable for CD patients. We tested the long-term efficacy and safety of colecalciferol and calcium with sodium-fluoride or i.v. ibandronate for osteoporosis in CD. Methods: 66 CD patients with lumbar osteoporosis (T-score
