o
re
itt
s on
itt
re a
C. R.Revankar * and A.P.Dash**
rs
Li ce ns e
m
C om
e
tiv
ed
:U
se
Pe r
un de rC
m
Changing epidemiological presentation in Dengue infection in South-East Asia Region
m
C om
tiv 1,2 4 7 52 7,8 4 3
1,2 0 2 1,2 3 5
200,000
C om
e
1,0 9 7 1,0 3 5
tiv
300,000
1,500
No of Deaths
rC No of Cases
de un ed
1,53 2
1,000 887
3 3 7,19 2 2 8 0 ,552 2 50 ,50 9 500 2 11,0 3189 8 ,2 12 100,000 18 9 ,8 3 0 179 ,9 177,0 58 14 0 ,6 152 3 5 ,50 3 6 3 ,6 72 0 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011
rC
m
itt
re a
6 56
Non-endemic
de
Pe r
Years
un
se
ed
U
itt
te rs :
m
CONCLUSIONS
Pe r
Po s
r
de
itt
rs
ed
:U
un
se
0
00
F1
10
:U
00
se
Pe r
Po s
m
te
se .
ce n
te
rs
.F
00
se
Pe r
Po s
ns e
ce
Li
:U
10
s
Li
10 00
Po s
ce ns
te
rs
e. F
on
s
.F
on m
ce
00
ns e
om
rC
m
on
s
.F 10
e
re at iv
1.Changing epidemiology of dengue in South-East Asia: Rajesh Bhatia et al. WHO South-East Asia Journal of Public Health | January-March 2013
Li
C
om
ns e
REFERENCES
Po s
m
om
C
e
at iv
at iv
e
Li ce
C
de
un
ed
rC
m
re
on s
ACKNOWLEDGEMENTS AND CONTACT
om
The authors are thankful to all the members of the team for their support. Contact:
[email protected]
C
re
at iv
e
C
de
un
itt ed
1,78 5
1,76 6
400,000
2 ,0 3 1 2,000 1,8 59
The major factors influencing changes in dengue epidemiology are i) viral genotypes/subtypes with increased virulence; ii) lack of information on human population genetics and its relation with viral genome; iii) lack of information on vector ecology in micro-climatic conditions; iv) viral load injected by infected mosquito; v) post-infection natural immunity of the host and vi) time interval in sequential infection.
itt
rm
500,000
2. Dash AP: Personal communication. 2014
m
Pe r
se
U
s: st er
2,500
The health programme managers may consider looking at the changing patterns to implement control / prevention measures to reduce the disease burden and its impact. Appropriate operational and implementation research issues are to be to identified in addition to basic research to effectively control dengue.
re
rC
de
un
itt ed
rm
Pe
se
U
s:
te r
re a
ed Pe rm
Po st e
00
Li
s
de
un
d
itt e
rm
Pe
Po s
Deaths
The vectors are very adaptive in nature and have been affected by climatic changes, socio-cultural and economic factors, and rapid urbanization
on
m
om
C
iv e
at
re rC
The maximum burden of the infection (dengue /dengue hemorrhagic fever) occurred in the 10 out of 11 Member countries of the SEA Region. A total 2.4 million cases were reported from 2000 to 2011 in the region. Though cases are declining in the Region since 2011, there is a upsurge in dengue cases in Thailand and Sri Lanka. However, the case fatality rate is declining in the member countries. Age and sex-wise analysis of trend data showed a shift in the affected age groups and sex groups. More cases were reported among the adults than children
