May 14, 1998 - A commercially available slide agglutination test (SAT) for the .... carried out by McNemar's test (7), with significance levels set at 0.05 and 0.01.
JOURNAL OF CLINICAL MICROBIOLOGY, Nov. 1998, p. 3138–3142 0095-1137/98/$04.0010 Copyright © 1998, American Society for Microbiology. All Rights Reserved.
Vol. 36, No. 11
Macroscopic Agglutination Test for Rapid Diagnosis of Human Leptospirosis ˜ O,1,2 EIDE D. CAMARGO,3* EMILSON D. ANGELA P. BRANDA ˜ O1 MARCOS V. SILVA,4 AND RUI V. ABRA
DA
SILVA,1
Fundac¸a ˜o Oswaldo Cruz, Rio de Janeiro, RJ,1 Fundac¸a ˜o Nacional de Sau ´de, Sa ˜o Paulo, SP,2 Instituto Adolfo Lutz, Sa ˜o Paulo, SP,3 and Instituto de Infectologia Emı´lio Ribas, Sa ˜o Paulo, SP,4 Brazil Received 9 March 1998/Returned for modification 14 May 1998/Accepted 4 August 1998
A commercially available slide agglutination test (SAT) for the diagnosis of human leptospirosis was evaluated by comparing it to an immunoglobulin M (IgM) enzyme-linked immunosorbent assay (ELISA) and to the microscopic agglutination test (MAT). For all 108 patients, leptospirosis was diagnosed on the basis of a fourfold or greater increase in titer by MAT (seroconversion), and all but 1 of 245 controls were MAT negative (titers,
