Multimeric complement component C9 is necessary for ... - Europe PMC
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Version 1 Last Updated 20 November 2013. Instructions for Use. For the
quantitative measurement of Complement C9 in Human plasma, serum, saliva,
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Multimeric complement component C9 is necessary for ... - Europe PMC
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Proc. Natl. Acad. Sci. USA Vol. 82, pp. 4808-4812, July 1985 Medical Sciences
Multimeric complement component C9 is necessary for killing of Escherichia coli J5 by terminal attack complex C5b-9 [poly(C9)/complement-mediated bacterial killing]
K. A. JOINER*, M. A. SCHMETZ*, M. E. SANDERS*, T. G. MuRRAY*, C. H. HAMMER*, R. DOURMASHKINt, M. M. FRANK*
AND
*Labortory of Clinical Investigation, National Institutes of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20205; and tSt. Bartholemew's Hospital, London, England
Communicated by William E. Paul, March 22, 198S
bacterial killing may differ from the form necessary for erythrocyte lysis. The molecular stoichiometry of C9 within the terminal complement complex is variable. The input of C9 influences the size of the transmembrane channel produced, with channel diameters varying from