Personalized AI-Based Asthma Management

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and symptom tracking. Families. Assess. Improve. Asthma. Educators. Efficiently track patients, can proactively outreach
Personalized AI-Based Asthma Management

Tueo solution: Personalized, AI-based Asthma Management Program Collect

Assess

Improve

Families

Data driven alerts with personalized education, actionable next steps and symptom tracking Physiologic Data through Contactless Nocturnal Monitoring Daily Assessment

Environmental Data

Asthma Educators Efficiently track patients, can proactively outreach, address questions or concerns

Passive, data driven, personalized chronic disease management

Passive Data Source

Data Collected

Insights about clinical status

Actionable next steps

Insights

Intervention

Improved outcomes

50% of Asthma Cases are Not Well Controlled

25M Americans have Asthma

$56B/yr Healthcare expenditures with majority of costs from preventable emergency-based care

Why do we care about maintaining control? Very poor

Not Well

Severe exacerbation

>3x

$4,000/yr

likelihood to have ER visit or hospitalization

increased healthcare costs

Well Control Scale and Exacerbation Risk

Asthma is a complex disease, but many measurable drivers and signs Signs that can be measured

Measurable Drivers

Allergen Virus Pollution

Asthma Control

Sleep quality Nighttime awakenings

Heart rate Heart rate variability

Respiratory rate

Cough frequency

Weather Medications

Prior observational study demonstrating: Heart rate changes days before an exacerbation

ACAAI abstract, 20161

Heart rate changes correlate with asthma control

ATS abstract, 20172

87% accuracy predicting asthma symptoms

AJRCCM, 2018

Actionable insights • Alert engages the patient/caregiver • Additional context gained • Symptom/control tracking • Timely, targeted education Next steps: • Identify trigger • Consider personalized coaching intervention • Share information with medical team

Achieving guidelines for asthma management Assessment and Monitoring

Assess asthma control to determine if therapy should be adjusted

Use of Meds Select medication and delivery devices that meet patient’s needs Review medications, technique, and adherence at each follow-up visit.

https://www.nhlbi.nih.gov/files/docs/guidelines/asthma_qrg.pdf

Asthma Education

Control of Environment

Teach patients how to manage their asthma.

Recommend ways to control exposures to allergens, irritants, and pollutants that make asthma worse.

Integrate education into all points of care

Clinically validated to improve outcomes and reduce healthcare spending •260 pediatric asthma patients, 16 week, randomized controlled study •In partnership with Evidation Health

Significant clinical improvement seen in asthma control*

93% of users interact with app after receiving a significant alert*

Estimated $2800/yr avg healthcare savings* *Preliminary study results

Individual 9 yo patient example

The year prior to using Tueo Service: >10 exacerbations in the past year 2 emergency room visits 1 hospitalization

Estimated yearly cost: >$7,000

3 Months with Tueo November

December

January

Final Results

3 months using the Tueo Service: 1 exacerbation 0 emergency room visits 0 hospitalization

“When his levels change at night and I don't know why, within 2 days he has a bad attack. Its just amazing how much I have learned with this trial …the doctor loves looking at everything too. You have been an amazing help with me learning how to deal with this all.”

– Mom of a 9 year old boy (Clinical study participant)

Launching subscription service B2C as B2B sales ramp 2018

B2B B2C Paid Pilot Soft Launch Pediatric Asthma

2019

2020

B2B Pilots Convert to Contracts B2C Launch

B2B Contracts

Adult asthma

then expanding to adults with asthma and COPD

B2B Contracts COPD Chronic obstructive pulmonary disease

Thank-you!