RCPath - RCC-MGP case.pptx

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Dec 18, 2018 - Female, 51 years old. • Hematuria. • Kidney mass, 5.5cm extending microscopically to hilar renal soft tissues. • Tubular, cribiform, and solid ...
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Dec 18, 2018

•  Previous history of leiomyomatosis

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•  Female, 51 years old. •  Hematuria. •  Kidney mass, 5.5cm extending microscopically to hilar renal soft tissues. •  Tubular, cribiform, and solid growth pattern. •  Desmoplastic reaction •  Large cell with prominent nucleolus and eosinophilic cytoplasm •  Microscopic vascular invasion. •  Margins free of neoplasm (circumferential, ureteric and vascular)

Dec 18, 2018

Renal Cell Carcinoma

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RCC case

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Dec 18, 2018

100K Genomes Project

Dec 18, 2018

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RCC case 12/18/18

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Dec 18, 2018

100K Genomes Project

Dec 18, 2018

100K Genomes Project

RCC case 12/18/18

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TUMOR TYPE: KIDNEY RENAL CELL CARCINOMA, UNCLASSIFIED

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RCC case

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Dec 18, 2018

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Renal Cell carcinomas, unclassified vascular

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New Phenotype of Pseudohypoxia-associated Neoplasms – Low mutation burden and solid, desmoplastic, poorly-differentiated growth

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Dec 18, 2018

Pseudohypoxia Pathways

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RCC case

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100K Genomes Project

Dec 18, 2018

Neoangiogenesis and Tumorigenesis Promotion in Pseudohypoxia

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RCC case

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