Feb 14, 2006 - We also thank Joe Fernandez and the Proteomic Resource Center of The. Rockefeller University for protein sequence analysis. This work was.
Simple fold composition and modular architecture of the nuclear pore complex Damien Devos*, Svetlana Dokudovskaya†, Rosemary Williams†, Frank Alber*, Narayanan Eswar*, Brian T. Chait‡, Michael P. Rout†§, and Andrej Sali*§ *Departments of Biopharmaceutical Sciences and Pharmaceutical Chemistry and California Institute for Quantitative Biomedical Research, University of California, Mission Bay QB3, 1700 4th Street, Suite 503B, San Francisco, CA 94143-2552; and Laboratories of †Cellular and Structural Biology and ‡Mass Spectrometry and Gaseous Ion Chemistry, The Rockefeller University, 1230 York Avenue, New York, NY 10021-6399 Edited by Peter Walter, University of California School of Medicine, San Francisco, CA, and approved December 23, 2005 (received for review July 26, 2005)
The nuclear pore complex (NPC) consists of multiple copies of ⬇30 different proteins [nucleoporins (nups)], forming a channel in the nuclear envelope that mediates macromolecular transport between the cytosol and the nucleus. With
