Suppl Fig 4

Suppl Fig 4 a.

Human diploid lung fibroblasts (DLFs) SBB Late passages (Senescence)

bi.

GL13 Late passages (Senescence)

Bleomycin induced lung fibrosis mouse model SBB Senescent Pneumonocytes

GL13 Irradiated (Senescence)

GL13 Tet-ON (Senescence)

SaOs p53Tet-ON SBB Tet-ON (Senescence)

GL13 Tet-ON (Senescence)

SBB Xenograft

bii.

GL13 Tet-ON (Senescence)

U2OS E2F1-ER SBB 4-OH-Tamoxifen + (Senescence)

GL13 4-OH-Tamoxifen + (Senescence)

GL13 Xenograft

Human laryngeal tissue GL13 Irradiated

SBB Irradiated

Human breast tissue

U2OS hCdt1 Tet-ON SBB Tet-ON (Senescence)

GL13 Senescent Pneumonocytes

Palbociclib induced tumor (melanoma) senescence mouse model

SaOs p21WAF1/Cip1 Tet-ON SBB Tet-ON (Senescence)

GL13 Adenoma

SBB Adenoma

Human diploid lung fibroblasts (DLFs) SBB Irradiated (Senescence)

Mouse model conditionally expressing K-rasV12 in the lung

SBB Irradiated

GL13 Irradiated

Human melanocytic lesion SBB Congenital nevous

GL13 Congenital nevous