Visual detection and characterization of chronic ... - Springer Link
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Visual detection and characterization of chronic ... - Springer Link
Feb 3, 2015 - Breath-held 2D native T1 maps (8 TIs with 2 Look-Locker cycles of 3+5 images; minimum TI = 120ms; TI increment. = 80 ms; flip angle = 35°; ...
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ORAL PRESENTATION
Open Access
Visual detection and characterization of chronic myocardial infarctions in patients using native T1 maps at 3T Avinash Kali1*, Eui-Young Choi2, Behzad Sharif1, Young Jin Kim2, Xiaoming Bi3, Bruce S Spottiswoode3, Ivan Cokic1, Hsin-Jung Yang1, Mourad Tighiouart1, Debiao Li1, Daniel S Berman1, Byoung Wook Choi2, Hyuk-Jae Chang2, Rohan Dharmakumar1 From 18th Annual SCMR Scientific Sessions Nice, France. 4-7 February 2015 Background Late Gadolinium Enhancement (LGE) Cardiovascular Magnetic Resonance (CMR) is routinely used for characterizing chronic myocardial infarctions (cMIs), but it is contraindicated in patients with end-stage chronic kidney disease. We investigated whether native T1 mapping at 3T can be used to detect and characterize cMIs in patients with prior STEMI and NSTEMI. Methods Breath-held 2D native T1 maps (8 TIs with 2 Look-Locker cycles of 3+5 images; minimum TI = 120ms; TI increment = 80 ms; flip angle = 35°; bandwidth = 1085 Hz/pixel; voxel size = 1.5x1.5x8mm3) and LGE images (IR-prepared FLASH; optimal TI to null remote myocardium; TR/TE = 6.54/3.27ms; flip angle = 20°; bandwidth = 460 Hz/pixel; voxel size = 1.2x1.2x8mm3) were acquired in patients with prior STEMI (n=15) and NSTEMI (n=17) at 3T at a median of 13.6 years after acute MI. cMI location, size and transmurality were determined using Mean+5SD criterion relative to remote myocardium. Visual detection of cMI territories on LGE images and T1 maps were assessed by two independent reviewers. Results Representative native T 1 maps and LGE images from two patients, one with prior STEMI, and one with prior NSTEMI are shown in Fig. 1. Relative to remote myocardium, median T 1 of the cMI was 271ms higher in STEMI patients (Infarct: 1517ms; Remote: 1247ms; 1 Cedars-Sinai Medical Center, Los Angeles, CA, USA Full list of author information is available at the end of the article
