Gregg Martin Schieffer - Houk Research Group - Iowa State University

Gregg Martin Schieffer [email protected] Home Address: 2707 Luther Dr. # 7 Ames, IA 50010-4784 (515) 441-0180

Office Address: 3334 Gilman Hall Ames, IA 50011-3111 (515) 294-4285

Education PhD Candidate in Analytical Chemistry Iowa State University, Ames, IA

2004-present

Bachelor of Science in Chemistry, Cum Laude University of St. Thomas (UST), St. Paul, MN

2000-2004

Research Experience Ion mobility and mass spectrometry of biomolecules Develop methods to analyze coal degradation products Plant metabolite analysis using AP-LDI mass spectrometry High speed GC using novel aromatic selective laser ionization detector (ArSLID)

2004-present 2008-present 2006-2008 2003-2004

Relevant Skills Mass Spectrometry • Instrumentation: Home-built Ion trap – Ion mobility – qTOF MS, Varian 1200L triple quad mass spectrometer, Thermo LCQ-Advantage ion trap mass spectrometer & TSQ7000 triple quad mass spectrometer, Agilent 1100 series ion trap mass spectrometer, HP 5890 GC single quad mass spectrometer, Jeol AccuTOF • Ionization techniques: Electrospray (ESI), nano-ESI, atmospheric sampling glow discharge ionization, atmospheric pressure chemical ionization, laser desorption ionization (LDI), matrix assisted-LDI (MALDI), electron impact (EI), direct analysis real time (DART) • Griffin Analytical Technologies Argos instrument controller, vacuum implementation (Edwards, Varian, and Pfeiffer pumps), DEI pulse generators, Ortec power supplies (PS), Extrel RF PS, Keithley picoammeter, Agilent oscilloscope • Build, operate, and maintain mass spectrometers – specifically ion traps, ion mobility, ion funnels, and TOF Separations • Varian, Dionex, and Agilent HPLCs • Separated coal compounds

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Polymer Labs PL-ELS-2100 evaporative light scattering detector

Gas chromatography / Liquid chromatography • Perkin-Elmer Autosystem GC equipped with a photoionization detector and ArSLID • Hewlett Packard 5890 GC equipped with a flame ionization detector • High speed VOCs (BTEXI) separation Computer skills / Miscellaneous • Microsoft Office (2003-2007), Endnote, MATLAB, AutoCAD, LabVIEW, IGOR, maintaining lab’s computer network and website • Safety and chemical waste management Graduate Classes • Advanced Quantitative Analysis • Analytical Separations, incl. chiral separations • Analytical Spectroscopy • Group Theory

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Electrochemical Methods of Analysis Mass Spectrometry Spectrochemical Identification of Organic Compounds

Awards GAANN Fellowship Recipient, 2008-2009 (ISU) American Institute of Chemists Award for Outstanding Chemistry Majors, 2003 (UST) Aquinas Scholar, 2000-2004 (UST) Collaborative Inquiry Grant, Spring 2003 & 2004 (UST)

William Larson Scholarship Recipient, September 2003 – May 2004 (UST) Analytical Chemist of the Year 2003 (UST) Eagle Scout (Boy Scouts of America, 1999) Professional Affiliations: American Chemical Society American Society for Mass Spectrometry Academic Affiliations: Phi Lambda Upsilon Honorary Chemical Society Publications: 3. Zhao, Q., Soyk M. W., Schieffer G. M., Houk, R. S., Badman, E. R.; “An Ion Trap – Ion Mobility – TOF Instrument with Three Ion Sources to Enable Ion-Ion Reactions” (submitted to JASMS, Jan. 2009) 2. Zhao, Q., Soyk M. W., Schieffer G. M., Houk, R. S., Badman, E. R.; “A Method to Separate Protein Ions with Similar Ion Mobilities via Mass-Selective Ejection from an Ion Trap” (paper in preparation) 1. Meyer, M. J.; Schieffer, G. M.; Moeker, E. K.; Brodersen, J. J.; Swenson, O. F.; Borgerding, A. J.; “Selective Detection of Volatile Aromatic Compounds Using a Novel Laser Ionization Detector with Fast Gas Chromatography” Anal. Chem. 2004, 76, 1702-1707. Selected Poster Presentations: 10. “Atmospheric Pressure Laser Desorption/Ionization Using Colloidal Graphite and Silver Colloid for the Determination of Plant Metabolites” D. C. Perdian, Gregg M. Schieffer, R. S. Houk, 56th ASMS Conference on Mass Spectrometry, Denver, CO, June 1st-5th, 2008 9. “Determining Plant Metabolites by Collision Induced Dissociation (CID) and AP-MALDI” Gregg M. Schieffer, David C. Perdian, Ethan Badman, R.S. Houk, 55th ASMS Conference, Indianapolis, IN, June 3rd-June 7th, 2007. 8. “Ion-Ion Reactions using a Home-Built, Research-Grade Linear Ion Trap Mass Spectrometer” Matthew W. Soyk, Qin Zhao, Gregg Schieffer, R.S. Houk, Ethan Badman, 55th ASMS Conference, Indianapolis, IN, June 3rd-June 7th, 2007. 7. “A Combination of Ion-Ion Reaction and Ion Mobility Measurement for Top-Down Protein Analysis” Qin Zhao, Matthew Soyk, Gregg Schieffer, Ethan Badman, R.S. Houk, 55th ASMS Conference, Indianapolis, IN, June 3rd-June 7th, 2007. 6. “A Method to Separate Protein Ions with Similar Ion Mobilities via Mass-Selective Ejections from an Ion Trap” Qin Zhao, Matthew W. Soyk, Gregg M. Schieffer, Ethan R. Badman, 54th ASMS Conference, Seattle, WA, May 28th-June 1st, 2006. 5. “A Research-Grade ESI-Linear Ion Trap Mass Spectrometer for Ion-Ion Reactions using Commercial Components” Matthew W. Soyk, Qin Zhao, Gregg M. Schieffer, Ethan R. Badman, 54th ASMS Conference, Seattle, WA, May 28th-June 1st, 2006. 4. “An ESI-Ion Trap-Ion Mobility-q-TOF to Study Ion-Ion Reactions of Intact Biopolymers” Ethan Badman, Gregg M. Schieffer, Matthew W. Soyk, Qin Zhao, Tim J. Anderson, 53rd ASMS Conference, San Antonio, TX, June 5-9, 2005. 3. “Improving the Temperature Range of the Aromatic Selective Laser Ionization Detector” G. M. Schieffer, A. J. Borgerding, 25th Annual Symposium of the Minnesota Chromatography Forum, Brooklyn Park, MN, May, 2004. 2. “Rapid Measurements Using an Aromatic Specific Laser Ionization Detector (ArSLID)” A. J. Borgerding, G. M. Schieffer, M. J. Meyer, O. J. Swenson, 26th International Symposium on Capillary Chromatography and Electrophoresis, Las Vegas, NV, May, 2003. 1. “Comparing the Selectivity of the Aromatic Selective Laser Ionization Detector with a Photo-ionization Detectors for Analysis of VOCs” G. M. Schieffer, M. J. Meyer, A. J. Borgerding, Minnesota Academy of Sciences Research Symposium, Minneapolis, MN, April, 2003.