Interference of cell cycle progression by zidovudine and lamivudine in ...
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Interference of cell cycle progression by zidovudine and lamivudine in ...
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Interference of cell cycle progression by zidovudine and lamivudine in NIH 3T3 cells
Jia-Long Fang*, Lynda J. McGarrity1 and Frederick A. Beland Division of Biochemical Toxicology and 1Division of Genetic and Reproductive Toxicology, National Center for Toxicological Research, Jefferson, AR 72079, USA
Zidovudine (3#-azido-3#-deoxythymidine; AZT) and lamivudine [(2)2#,3#-dideoxy-3#-thiacytidine; 3TC] are nucleoside reverse transcriptase inhibitors used to treat and prevent human immunodeficiency virus-1 infections. In short-term incubations (