1
High progesterone levels at farrowing impair colostrum IgG concentration and colostrum yield in sow INTRODUCTION
Hasan SMK 2 Junnikkala S 1 Peltoniemi O 1 Oliviero C
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Department of Production Animal Medicine, 2 Department of Veterinary Biosciences Faculty of Veterinary Medicine, P.O. Box 57, 00014 University of Helsinki, Finland
[email protected]
RESULTS
Lactogenesis is induced hormonally by a dramatic drop
IgG in colostrum
of progesterone (P4) concentrations which leads to a pre-partum peak of prolactin (PRL). In sows, impaired a delay in the decrease of P4 concentrations during the pre-partum period. We assumed that this condition might affect also the
IgG mg/ml
production of colostrum has been found to be related to
90 80 70 60 50 40 30 20 10 0
quality of colostrum (IgG concentration). Our aim was to investigate the relationship between abnormally high
low p4
high p4
Fig. 1. Effect of high P4 on colostrum IgG concentration
P4 levels at parturition with colostrum yield (CY) and its IgG content in sows.
ü Sows having values of P4 > 4.00 ng/ml had lower IgG in colostrum (52.75 mg/ml vs 66.56 mg/ml; p = 0.01).
Colostrum yield
MATERIALS & METHODS 6000
Sample collection
assess P4 concentration at the beginning of parturition.
CY (g)
Ø Blood samples (n=38) from vena saphena medialis to
5000 4000 3000 2000 1000 0
Ø Colostrum samples (n=38) were obtained between 0-3 h after the birth of first piglet. Ø Individual piglets' weight at 0 and 24 h of age
low p4
high P4
Fig. 2. Effect of high P4 on colostrum yield in sow ü Sows having values of P4 > 4.00 ng/ml had lower average CY (2125±1779 g vs 4114±1155 g ; p=0.01).
CONCLUSIONS Sample analysis & criteria v Sows with an abnormal high P4 concentration at Ø Plasma P4 concentrations by RIA at lab and values were grouped P4> 4.0 ng/ml (high p4 ) and P4< 4.0 ng/ml (low p4) Ø Colostrum IgG by pig ELISA Ø Colostrum production by weight suckle weight method
farrowing tended to have lower IgG content and CY, which might indicate hormonal disruption during the farrowing, with potential negative effects on piglets colostrum uptake.
