Sunday, July 22 2018. 2:00 pm - 9:00 pm. Arrival and Check-in. 6:00 pm. Dinner. 7:30 pm - 7:40 pm. Welcome / Introductory Comments by GRC Site Staff.
2018 GRC DRUG RESISTANCE MEETING
Looking for Common Themes and Solutions in Drug Resistance For Cancer, Infectious Disease and Agriculture http://www.grc.org/programs.aspx?id=15067
Chairs: J. Singh & J.A. Silverman Vice Chair: M. Cynamon
July 22nd - 27th, Bryant University, RI, USA
E. coli ribosome from Goddard 2017 UCSF
Sunday, July 22 2018 2:00 pm - 9:00 pm
Arrival and Check-in
6:00 pm
Dinner
7:30 pm - 7:40 pm
Welcome / Introductory Comments by GRC Site Staff
7:40 pm - 9:30 pm
Keynote Session: Discussion Leaders: Jared Silverman (Kaleido Biosciences, USA)
7:40 pm - 8:20 pm
Vance Fowler (Duke, USA) Antibacterial Resistance and the Antibacterial Resistance Leadership Group: Problems, Innovations, and Productivity
8:20 pm - 8:35 pm
Discussion
8:35 pm - 9:15 pm
Stephen Fawell (Astra Zeneca, USA) Challenges and Opportunities in Cancer Drug Resistance
9:15 pm - 9:30 pm
Discussion
Monday, July 23 2018
7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Modeling of Resistance Discussion Leader: Dominik Wodarz (UC Irvine, USA)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:35 am
Natalia Komarova (UC Irvine, USA) Stochastic Modeling of Drug Resistance in Cancer
9:35 am – 9:50 am
Discussion
9:50 am – 10:20 am
Bruce Levin (Emory, USA) The Within-Host Pharmaco-Population- and Immune-Dynamics of Antibiotic Treatment and the Evolution of Resistance
10:20 am – 10:35 am
Discussion
10:35 am – 10:55 am
Coffee Break
10:55 am – 11:25 am
Paul Neve (Rothamsted, UK) Evolution of Herbicide Resistance in Global Agroecosystems: From Gene to Landscape
11:25 am – 11:40 am
Discussion
11:40 am - 11:55 am
Short Talk Selected from Poster Abstracts #1
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:20 pm
Short Talk Selected from Poster Abstracts #2
12:20 pm - 12:30 pm
Discussion
12:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm
Dinner
7:30 pm - 9:30 pm
New and Emerging Drug Resistance Mechanisms Discussion Leader: Priscilla Yang (Harvard, USA)
7:30 pm – 7:55 pm
Shawn Lockhart (CDC, USA) Simultaneous Emergence of Multidrug-Resistant Candida auris on 3 Continents
7:55 pm - 8:10 pm
Discussion
8:10 pm – 8:35 pm
TBD
8:35 pm – 8:50 pm
Discussion
8:50- pm - 9:15 pm
Tanguy Seiwert (Univ Chicago, USA) Immunotherapy and Drug Resistance
9:15 pm- 9:30 pm
Discussion
Tuesday, July 24 2018 7:30 am - 8:30 am
Breakfast
8:30 am
Group Photo
9:00 am - 12:30 pm
Tackling Resistance in Discovery and Development For Cancer Discussion Leader: Michael Cynamon (SUNY- Upstate, USA)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:35 am
Erica Evans (Blueprint Medicines, USA) Building Kinase Inhibitor Programs with Resistance in Mind
9:35 am – 9:50 am
Discussion
9:50 am – 10:20 am
Sara Buhrlage (Dana Faber, USA) Novel Strategies To Induce Degradation Of Leukemia Oncogenes
10:20 am – 10:35 am
Discussion
10:35 am – 10:55 am
Coffee Break
10:55 am – 11:25 am
Daruka Mahadevan (Univ of Arizona Cancer Center, USA) Anti-Evolution Therapies for Cancer
11:25 am – 11:40 am
Discussion
11:40 am - 11:55 am
Short Talk Selected from Poster Abstracts #3
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:20 pm
Short Talk Selected from Poster Abstracts #4
12:20 pm - 12:30 pm
Discussion
12:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm
Dinner
7:30 pm - 9:30 pm
Tackling Resistance in Discovery and Development For Anti-Infectives Discussion Leader Aaron Goldman (MIT)
7:30 pm – 7:55 pm
Ann Kwong (Trek Therapeutics, USA) HCV Is The Only Viral Infection That Can Be Cured – Harbinger Of The Future Or A Unicorn?
7:55 pm - 8:10 pm
Discussion
8:10 pm – 8:35 pm
Tim van Opijnen (Boston College) Predicting Antibiotic Resistance Through Microfluidics, Single Cell-Analysis, Omics-Approaches, Experimental Evolution And Full-Genome Modeling
8:35 pm – 8:50 pm
Discussion
8:50- pm - 9:15 pm
Paul Ambrose (ICPD, USA) Antimicrobial Replication Rate Modulation: Turning the Microbe Against Itself
9:15 pm- 9:30 pm
Discussion
Wednesday, July 25 2018 7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
New Approaches to Drug Resistance Discussion Leader: Manuel Navia (Hub-Bio, USA)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:35 am
John Overington (Catapult, UK) Drug Blending As An Approach To Tackling Resistance
9:35 am – 9:50 am
Discussion
9:50 am – 10:20 am
Cassandra Quave (Emory, USA) Medical Ethnobotany and the Discovery of New Drugs to Combat Resistance
10:20 am – 10:35 am
Discussion
10:35 am – 10:55 am
Coffee Break
10:55 am – 11:25am
Jean-Marie Pages (Aix-Marseille Université , Marseille) Antibiotic Translocation and Membrane Barrier: New tools to Dissect the Bacterial Resistance
11:25 am – 11:40 am
Discussion
11:40 am - 11:55 am
Short Talk Selected from Poster Abstracts #5
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:20 pm
Short Talk Selected from Poster Abstracts #6
12:20 pm - 12:30 pm
Discussion
12.30 pm
Lunch
6:00 pm
Dinner
7:00 pm - 7:30 pm
Business Meeting: Next Vice Chair; Conference Evaluations; Future Site and Scheduling Preference
7:30 pm - 9:30 pm
A Century Beyond the Spanish Flu – Addressing Pandemic Threats Discussion Leader: Carolyn Shore (Pew Charitable Trust, USA)
7:30 pm - 7:35 pm
Introduction by Discussion Leader
7:35 pm – 9.30 pm
TBD
Thursday, July 26 2018 7:30 am - 8:30 am
Breakfast
9:00 am - 12:30 pm
Heterogeneity Discussion Leader: Alexis Kaushansky (CIDR, Seattle, USA)
9:00 am - 9:05 am
Introduction by Discussion Leader
9:05 am - 9:35 am
Andriy Marusyk (Moffit Cancer Center, USA) Intra-tumor Heterogeneity in Resistance to Targeted Cancer Therapies
9:35 am – 9:50 am
Discussion
9:50 am – 10:20 am
John Aitchison (CIDR Seattle, USA) Network Biology and Infectious Disease
10:20 am – 10:35 am
Discussion
10:35 am – 10:55 am
Coffee Break
10:55 am – 11:25 am
Paul Mischel (UC San Diego, USA) In Cancer, as in Real Estate, Location Matters – The Role Of Extrachromosomal Oncogene Amplification In Cancer
11:25 am – 11:40 am
Discussion
11:40 am - 11:55 am
Short Talk Selected from Poster Abstracts #7
11:55 am - 12:05 pm
Discussion
12:05 pm - 12:20 pm
Short Talk Selected from Poster Abstracts #8
12:20 pm - 12:30 pm
Discussion
12:30 pm
Lunch
1:30 pm - 4:00 pm
Free Time
4:00 pm - 6:00 pm
Poster Session
6:00 pm
Dinner
7:30 pm - 9:30 pm
Diagnostics Discussion Leader: Andrew Tomaras (Bacterioscan, USA)
7:30 pm – 7:55 pm
Shana Kelley (Univ Toronto, Canada) New Technologies For Rapid Infectious Disease Diagnosis
7:55 pm - 8:10 pm
Discussion
8:10 pm – 8:35 pm
Ellen Foxman (Yale, USA) Host-Response Based Testing In The Diagnosis Of Airway Infections
8:35 pm – 8:50 pm
Discussion
8:50- pm - 9:15 pm
TBD
Friday, July 27 2018 7:30 am - 9:30 am
Breakfast and departure
