Muc4âErbB2 Complex Formation and Signaling in ... - Semantic Scholar
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Muc4âErbB2 Complex Formation and Signaling in ... - Semantic Scholar
G. O., Zhu, H. J., Walker, F., Frenkel, M. J., and Hoyne, P. A. (2002). Crystal ... Horowitz, J. C., Lee, D. Y., Waghray, M., Keshamouni, V. G., Thomas, P. E.,. Zhang ...
Molecular Biology of the Cell Vol. 17, 2931–2941, July 2006
Muc4–ErbB2 Complex Formation and Signaling in Polarized CACO-2 Epithelial Cells Indicate That Muc4 Acts as an Unorthodox Ligand for ErbB2 Victoria P. Ramsauer,* Vanessa Pino,† Amjad Farooq,† Coralie A. Carothers Carraway,† Pedro J.I. Salas,* and Kermit L. Carraway* Departments of *Cell Biology and Anatomy and †Biochemistry and Molecular Biology, University of Miami School of Medicine, Miami, FL 33101 Submitted September 27, 2005; Revised March 14, 2006; Accepted April 11, 2006 Monitoring Editor: Ben Margolis
Muc4 serves as an intramembrane ligand for the receptor tyrosine kinase ErbB2. The time to complex formation and the stoichiometry of the complex were determined to be
