Staphylococcus lugdunensis Endocarditis Complicated by ... lugdunensis endocarditis in an 18-year-old woman with preexisting mitral valve prolapse ...
bloodstream infection involving Staphylococcus lugdunen- sis small-colony variants. Recurrent pacemaker-related bloodstream infection within a period of 10 ...
Oct 4, 2002 - Etienne, H. Grundmann, D. Jonas, G. T. Noordhoek, J. Dijkstra, A. van ... Hernandez, J. L., J. Calvo, X. Antolinez, F. Gutierrez-Rubio, and M. C..
Frequency of Isolation of Staphylococcus lugdunensis among. Staphylococcal Isolates Causing Endocarditis: a 20-Year Experience. ROBIN PATEL,1,2* ...
May 21, 1992 - Extensive testing revealed all of theseisolates to be S. lugdunensis. ... glass tissue grinder with a small amount of nutrient broth, and the homogenate ..... Performance standards for antimicrobial disk susceptibility tests, 4th ed.
lugdunensis, a coagulase-negative Staphylococcus species (CoNS), has recently emerged because of its rapidly progressive, invasive nature in infective ...
Jul 4, 2011 - genome contains a single prophage named fSL1 and 14 insertion sequences. It does not ... nensis N920143 and HKU09-01 are (1) the presence of two identical putative ..... collagen triple helix repeat; G5, G5 domain;. MucBP ...
Apr 11, 2011 - with an antiandrogen (bicalutamide), luteinizing hormone-re- leasing hormone blockade (goserelin), and diethylstilboestrol. Subsequently, he ...
A 54-year-old male traffic policeman with osteoarthrosis in the right hip was operated on with an uncemented hydroxyapatite-coated titanium alloy prosthesis ...
high-dose intravenous benzylpenicillin and genta- micin in a synergistic dose for suspected infective endocarditis. Transthoracic echocardiography (TTE).
Dec 24, 2017 - Complex CE with ACIOL and RLF; PPV 2 weeks after; persistent cornea ... pars plana vitrectomy; RD, retinal detachment; RLF, retained lens ...
May 19, 2017 - (ED) with complaints of worsening right hip pain over the past eight weeks. ... the joint space, and thickening of the obturator internus muscle.
ted with an intense headache, vomiting, and lethargy. Abnor- mal findings .... biol. 33:96â98. 10. Schnitzler, N., R. Meilicke, G. Conrads, D. Frank, and G. Haase.
May 29, 2008 - Infect. Dis. 35:E32âE34. 2. Crawford, F., and J. Ferrari. .... APMIS 101:802â804. 30. Sotutu, V., J. Carapetis, J. Wilkinson, A. Davis, and N. Curtis.
Use of Defibrinated Horse Blood in Blood Agar Plates. Staphylococcus ... cases of S. lugdunensis per year over the last 10 years in our laboratory (Table 1).
Amarillo, TX, USA. Abstract. A 57-year-old end stage renal disease patient on hemodialysis (HD) presented with sepsis secondary to right buttock abscess and ...
Mar 30, 2011 - bacteria, the Isd system permits the utilization of host heme as a source of nutrient iron to facilitate .... The best-fit model of amino acid substitution used in the ML ... near transporter (NEAT) domains as opposed to the single.
Aug 11, 2008 - ing Galen's vein that caused arteriovenous shunting and obstruction of ... aneurysmal malformation, but computed tomography revealed an ...
Feb 11, 2016 - Philipp Klaritsch,4 David Benjamin Lumenta,5 Robert Krause,6 and Dirk von ... swift action to protect the mother and her unborn child. 1.
Oct 20, 2011 - passive transfer of SEB-specific antibodies was also studied in .... evaluated with Bionumerics software (version 3.0; Applied Maths,. Ghent ..... from rhesus macaques. Genea. Isolate no. seg sei sem sen seo etd agr-1 agr-2.
Carretera Pachuca-Tulancingo Km. 4.5, 42183 Mineral de la Reforma, Hidalgo, Mexico; 2Laboratorio de Microbiologıa Sanitaria. Centro Universitario de.
Feb 16, 1973 - MARTIN LINDBERG1 AND RICHARD P. NOVICK. Department of ...... Rush, M. G., C. N. Gordon, R. P. Novick, and R. C.. Wamer. 1969.
Oct 17, 2017 - studying the pharmacokinetics properties of the phage. The main ... concerns the population dynamics of ecological predator-prey models and ...
Homogeneous behavior for the internalization ability in osteoblasts. - Biofilm formation capacities of S. lugdunensis species show a high intra-species variability.
Pathophysiological mechanisms of bone and joint infections of coagulase negative staphylococci: specific behavior of Staphylococcus lugdunensis Y. MAALI, L. D'ANTHOUARD, P. MARTINS-SIMÔES, A. MONTEIX, F. VALOUR, F. VANDENESCH, T. FERRY, F. LAURENT, S. TROUILLET-ASSANT
Figure 1 : The invasion of MG-63 cells was assessed by quantifying the viable intracellular bacterial loads at 3h postinfection after gentamicin treatment.
Optical density (620 nm)
Figure 3 : Biofilm formation by S. lugdunensis. A. Comparison of biofilm formation capacities between carriages and BJI strains. B. Multilocus sequence typing of S. lugdunensis isolates associated with their biofilm formation profiles. The strains are classified from non-producer to strong producer using the classification of Christensen et al., J Clin Microbiol, 1985.
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• Internalization capacity of each strain evaluated in MG63 osteoblasts using an in-vitro "Gentamicin protection assay" infection model. • Mature biofilm formation capacity measured in vitro using crystal violet staining after 24h of incubation. • Original data concerning the biofilm formation capacity of S. lugdunensis collected from BJI led us to integrate 10 S. lugdunensis strains isolated from nasal carriage as comparators. • Finally, the genetic diversity of S. lugdunensis isolates was analyzed using MLST (Multilocus sequence typing).
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Procedures overview • Clinical strains collected from monomicrobial BJI were studied: S. epidermidis (n = 5), S. haemolyticus (n = 3), S. lugdunensis (n = 7), S. capitis (n = 5), S. caprae (n = 5), S. warneri (n = 5).
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Associated to significant morbidity and mortality rates, bone and joint infections (BJI) are mainly due to staphylococci representing more than 60% of cases. Concerning S. aureus, two mechanisms of virulence have been associated with therapeutic failures: (i) internalization in non-professional phagocytic cells (NPPc), and (ii) biofilm formation. Conversely, little is known about the pathophysiological mechanisms of Coagulase-Negative Staphylococci (CoNS) involved in BJI despite their high prevalence. In this context, we decided to explore them.
- Homogeneous behavior for the internalization ability in osteoblasts. - Biofilm formation capacities of S. lugdunensis species show a high intra-species variability. - S. lugdunensis isolates collected from carriage have a significantly higher biofilm formation capacity than the clinical strains responsible for BJI (p
