additional file 3 2018 revised

Immunity

Signaling gene CG17336, Lcch3 CG6378, SPARC CG8394, VGAT CG18176, defl CG16827, ItgaPS4 CG3143, foxo CG3408 CG3022, GABA-B-R3 CG6357 CG10997, Clic CG3173, IntS1 CG5195, atk CG5372, ItgaPS5 CG10233, rtp CG4845, psidin CG4641,nwk CG17262, cnir CG8639, Cirl CG8909 CG8250, Alk CG7449, hbs CG1411, CRMP CG11335, lox CG4604, Glaz CG42611, mgl CG31221 CG15274, GABA-B-R1 CG34399, Nox CG9453, Spn42Da CG18870 CG11303, TM4SF CG17800, Dscam1 CG7446, Grd CG2736 CG6692, Cp1 CG8434, lbk CG31094, LpR1 CG13984 CG42613 CG11217, CanB2 CG3131, Duox CG10537, Rdl CG33126, Nlaz CG34370 CG6072, Sra CG4280, crq CG34385, dpr12 CG33950, trol CG7586, Mcr CG4636, SCAR CG4167, Hsp67Ba CG7000, snmp1 CG4096 CG4168 CG7228, pes CG31094, LpR1 CG4821, teq CG31619, nolo CG6817, foi CG1804, Kek6 CG12079, ND-30 CG18525, Spn88Ea CG14162, dpr6 CG12004 CG33087, LRP1 CG4545, SerT CG30361, mtt CG9623, if CG1618, comt CG8942, NimC1 CG10590, TM9SF3 CG7052, Tep2 CG1632 CG8743, Trpml CG11372, galectin CG1358 CG7509 CG30040, jeb CG8329 CG18525, Spn88Ea CG31092, LpR2 CG1771, mew CG2086, drpr CG6706, GABA-B-R2 CG42610, Fhos CG7563, CalpA CG1732, Gat CG6378, SPARC CG4099, Sr-CI CG8095, scb

212,48% 168,48% 141,03% 117,46% 109,47% 103,78% 101,19% 91,30% 82,35% 81,09% 74,74% 74,74% 73,21% 76,06% 73,67% 71,63% 70,19% 63,66% 62,50% 58,89% 55,33% 55,33% 53,95% 52,65% 50,00% 48,37% 47,15% 46,27% 44,36% 40,09% 36,76% 33,73% 33,14% 32,95% 32,62% 32,44% 32,41% 29,91% 29,26% 25,08% 24,36% 24,26% 24,26% 22,97% 22,75% 22,54% 21,57% 20,00% 19,17% 18,93% 18,74% 17,00% 16,04% 13,91% 9,55% 8,73% 8,33% 6,12% 6,05% 2,52% 1,67% -1,81% -5,38% -5,52% -10,78% -11,71% -12,63% -13,39% -13,80% -15,18% -21,85% -23,67% -24,42% -25,44% -30,71% -34,35% -40,55% -43,48% -45,83% -45,83% -48,30% -50,51% -51,37% -63,53% -63,53% -67,89%

VDRC s tock number 109606-KK 100566-KK 103586-KK 20604-GD 109783-KK 107786-KK 36306-GD 108036-KK 8782-GD 105975-KK 25825-GD 100110-KK 100120-KK 109000-KK 103558-KK 102133-KK 104009-KK 100749-KK 108629-KK 107083-KK 105913-KK 101510-KK 107435-KK 107433-KK 105071-KK 103017-KK 105863-KK 100753-KK 106306-KK 100135-KK 8847-GD 108835-KK 5329-GD 102672-KK 110619-KK 106679-KK 106364-KK 101831-KK 102823-KK 104370-KK 2593-GD 100429-KK 101321-KK 100162-KK 107573-KK 45883-GD 44741-GD 110494-KK 100197 KK 21908-GD 104341-KK 104210-KK 109025-KK 100080-KK 100391-KK 106364-KK 15362-GD 104736-KK 10102-GD 109681-KK 103412-KK 28340-GD 103521-KK 101732-KK 109605-KK 11346-GD 102982-KK 100770-KK 105552-KK 105799-KK 110679-KK 106997-KK 106107-KK 108088-KK 107054-KK 101453-KK 51584-GD 103047-KK 101603-KK 28340-GD 107597-KK 109608-KK 4833-GD 1785-GD 34035-GD 101294-KK 106638-KK 16678-GD 110014-KK 100949-KK

gene

VDRC s tock number

CG7121, Tehao CG5528, Toll-9 CG9681, PGRP-SB1 CG43119, Ect4 CG7250, Toll-6 CG7250, Toll-6 CG6531, wgn CG5490, Tl CG6794, Dif CG4432, PGRP-LC CG6667, dl CG1857, nec CG4437, PGRP-LF CG3048, Traf4 CG12919, egr CG13422, GNBP-like3 CG5008, GNBP3 CG12489, dnr1 CG33717, PGRP-LD CG7486, Dredd CG6134, spz CG11992, Rel CG14746, PGRP-SC1a CG6890, Tollo CG43119, Ect4 CG14928, SPZ-4 CG8896, 18w CG6890, Tollo CG8995, PGRP-LE CG11992, Rel CG11709, PGRP-SA

80,14% 66,80% 58,00% 54,79% 46,77% 42,69% 41,70% 38,64% 25,97% 12,80% 7,23% 0,17% -3,68% -4,02% -8,27% -8,82% -17,65% -20,49% -21,00% -23,20% -24,69% -30,75% -33,00% -33,90% -44,57% -45,35% -46,49% -49,84% -51,14% -56,70% -57,00%

109705-KK 109635-KK 101298-KK 102044-KK 27103-GD 928-GD 9152-GD 100078-KK 100537-KK 101633-KK 45996-GD 108366-KK 108313-KK 110766-KK 108814-KK 107358-KK 37256-GD 106453-KK 51023-GD 104726-KK 105017-KK 49414-GD 43201-GD 27099-GD 105369-KK 7679-GD 963-GD 9431-GD 108199-KK 49413-GD 5594-GD

220% 180% 120%

suppressors

60% 20% 0% -20% -40% -100%

enhancers lethal

Neuropeptides and Neuropeptide receptors gene CG14358, CCHa1 CG13758, Pdfr

VDRC s tock number 156,06%

104974-KK

85,75%

106381-KK

CG7665, Lgr1

77,92%

104877-KK

CG14375, CCHa2

73,21%

102257-KK

CG14734, Tk

63,59%

103662-KK

CG8784, PK2-R1

52,80%

103822-KK

CG7105, Proc

52,00%

102488-KK

CG10342, NPF

49,00%

108772-KK

CG2872, AstA-R1

46,70%

101395-KK

CG10698, CrzR

45,90%

108506-KK

CG13480, LK

44,00%

14091-GD

CG6438, amon

36,00%

110788-KK

CG32540, CCKLR-17D3

32,05%

102039 KK

CG6456, Mip

31,00%

106076-KK

CG5811, Rya-R

26,80%

103973-KK

CG7395, sNPF-R

25,90%

9379-GD

CG1147, NPFR

25,40%

9605-GD

CG30340

24,10%

100088-KK

CG13633, AstA

20,50%

103215-KK

CG13061, Nplp3

16,00%

105584-KK

CG40733, RYa

15,48%

109264-KK

CG7887, TkR99D

15,48%

43329-GD

CG3302, Crz

14,10%

102204-KK

CG3441, Nplp1

13,00%

14035-GD

CG14593, CCHa2-R

10,74%

100290-KK

CG7285, AstC-R1 CG13419, Burs

1,30%

110739-KK

-1,00%

111063-KK

CG10823, SIFaR

-11,80%

1783-GD

CG14575, CapaR

-12,41%

105556-KK

CG7285, AstC-R1

-14,41%

13560-GD

CG9918, PK1-R

-20,75%

101115-KK

CG8795, PK2-R2

-23,10%

100927-KK

CG6440, Ms

-27,00%

108760-KK

CG15520, capa

-28,00%

41124-GD

CG14919, AstC

-34,00%

102735-KK

CG6515,TkR86C

-37,64%

107090-KK

CG33696, CNMaR

-40,00%

101076-KK

CG30106, CCHa1-R

-40,56%

103055-KK

CG11051, Nplp2

-54,00%

15305-GD

Li_Dijkers Additional File 3