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Appendix A: Participants: Institution and Physician Institution

Physician

Aichi Medical University Hospital

Hiroaki Takashima, MD

Asahikawa-Kosei General Hospital

Takahiro Shiokoshi, MD

Ayase Heart Hospital

Hokko Memorial Hospital

Hidenari Hozawa, MD Kazuya Kawai, MD Shuichi Seki, MD Hiroshi Ohira, MD Yukio Ozaki, MD Hiroyuki Naruse, MD Sumio Mizuno, MD Kazuo Osato, MD Keijiro Saku, MD Hiroaki Nishikawa, MD Toshiyuki Noda, MD Makoto Iwama, MD Atsushi Sugiura, MD Yu Nakamura, MD Yoshiyuki Kijima, MD Akira Nishibe, MD Shigeo Umezawa, MD Yuko Onishi, MD Ken Okumura, MD Takumi Higuma, MD Yasuki Kihara, MD Satoshi Kurisu, MD Keiichi Igarashi, MD Kuniharu Nishimura, MD Yoichi Nozaki, MD

Hoshi General Hospital

Yoshitane Seino, MD

Iizuka Hospital

Japan Red Cross Okayama Hospital

Akira Yamada, MD Honin Kanaya, MD Toshihiko Yasuda, MD Hiroshi Ohta, MD Masafumi Sugi, MD Tomohiro Tada, MD Tomonori Itoh, MD Koichi Sano, MD Yasunari Ueno, MD Toru Obayashi, MD Takamichi Miyamoto, MD Tetsuya Sato MD

Japanese Red Cross Nagoya Daiichi Hospital

Haruo Kamiya, MD

Japanese Red Cross Kyoto Daini Hospital

Hiroshi Fujita, MD Takaaki Katsuki, MD Tomokazu Ikemoto, MD Katsumi Miyauchi, MD Ken Yokoyama, MD

Chikamori Hospital Edogawa Hospital Fujita Health University Hospital Fukui Cardiovascular Center Fukuoka University Hospital Gifu Prefectural General Medical Center Hekinan Municipal Hospital Higashiosaka City General Hospital Hiratsuka Kyosai Hospital Hirosaki University School of Medicine & Hospital Hiroshima University Hospital Hokkaido Social Insurance Hospital

Ishikawa Prefectural Central Hospital Itabashi Chuo Medical Center Iwaki Kyoritsu General Hospital Iwate Medical University Hospital Iwatsuki-minami Hospital Japan Red Cross Musashino Hospital

Jichi Medical University Hospital Juntendo University Hospital Juntendo University Nerima Hospital

Shinya Okazaki, MD

Juntendo University Shizuoka Hospital

Satoru Suwa, MD Ko Takeda, MD Masayuki Doi, MD Takahisa Noma, MD

Kagawa Prefectural Central Hospital Kagawa University Hospital Kanagawa Cardiovascular and Respiratory Center Kanazawa Cardiovascular Hospital Kansai Medical University Hirakata Hospital

Kazuki Fukui, MD Masanobu Namura, MD Hidenobu Terai, MD Hiroshi Kamihata, MD

Kimitsu Chuo Hospital

Masaki Awata, MD Atsuo Namiki, MD Masayuki Shibata, MD Hiroyuki Okura, MD Yoji Neishi, MD Yoshiaki Tsukamoto, MD Akio Kawamura, MD Yuichiro Maekawa, MD Akira Miyamoto, MD Masahiro Fukuda, MD Masashi Yamamoto, MD

Kitasato University Hospital

Taiki Tojo, MD

Kansai Rosai Hospital Kanto Rosai Hospital Kawasaki Medical School Hospital Kawasaki Saiwai Hospital Keio University Hospital Kikuna Memorial Hospital

Kobe University Hospital

Toshiro Shinke, MD

Kokura Memorial Hospital

Hiroyoshi Yokoi, MD

Kouseikai Hospital

Yoshihiro Iwasaki, MD

Koto Memorial Hospital

Teruki Takeda, MD Noriyuki Kinoshita, MD Katsushige Matsumoto, MD Katsuo Noda, MD

Koseikai Takeda Hospital Kumamoto Chuo Hospital

Institution Kumamoto Rosai Hospital Kurume University Hospital Kyoto-Katsura Hospital Mie Heart Center Miki City Hospital Mitsui Memorial Hospital Miyazaki Medical Association Hospital Japan Red Cross Nagoya Daini Hospital Nagoya Memorial Hospital Nara Medical University Hospital National Cerebral and Cardiovascular Center Nihon University Itabashi Hospital Nippon Medical School Chiba Hokusoh Hospital Nippon Medical School Hospital NTT Medical Center Tokyo Ogaki Municipal Hospital Oita Cardiovascular Hospital Oita Oka Hospital Okayama University Hospital Omihachiman Community Medical Center Osaka City University Hospital Osaka General Medical Center Osaka National Hospital Osaka Police Hospital Osaka Rosai Hospital Osaka University Graduate School of Medicine Rinku General Medical Center Saiseikai Imabari Hospital Saiseikai Kumamoto Hospital Saiseikai Yamaguchi Hospital Saiseikai Yokohama-city Eastern Hospital Saitama Medical University International Medical Center

Physician Hideki Doi, MD Takuo Tsurugi, MD Takafumi Ueno, MD Shinji Yokoyama, MD Shigeru Nakamura, MD Atsushi Funatsu, MD Hideo Nishikawa, MD Kojiro Awano, MD Kengo Tanabe, MD Shuzou Tanimoto, MD Yoshisato Shibata, MD Kensaku Nishihira, MD Haruo Hirayama, MD Mamoru Nanasato, MD Shigeru Katoh, MD Kazumasa Mori, MD Shiro Uemura, MD Kenichi Ishigami, MD Takafumi Yamane, MD Atsushi Hirayama, MD Tadateru Takayama, MD Yoshihiko Seino, MD Daisuke Murakami, MD Kyoichi Mizuno, MD Hitoshi Takano, MD Masao Yamasaki, MD Masashiro Matsushita, MD Hiroaki Mukawa, MD Tadafumi Akimitsu, MD Katsunori Tawara, MD Yoichi Tatsukawa, MD Masayuki Kaneko, MD Kengo Kusano, MD Kan Zen, MD Minoru Yoshiyama, MD Takao Hasegawa, MD Takahisa Yamada, MD Takashi Morita, MD Yoshio Yasumura, MD Masaki Yamato, MD Yasunori Ueda, MD Takayoshi Nemoto, MD Masami Nishino, MD Hiroyasu Kato, MD Shinsuke Nanto, MD Yuhei Nojima, MD Yoshiyuki Nagai, MD Yoshihiro Takeda, MD Tsutomu Mima, MD Satoshi Kawada, MD Koichi Nakao, MD Tomohiro Sakamoto, MD Shiro Ono, MD Toshiya Muramatsu, MD Hiroshi Ishimori, MD Tomomi Koizumi, MD

Sapporo Orthopaedics And Cardiovascular Hospital

Ryuta Asano, MD Keizo Yamamoto, MD Atsushi Hirohata, MD Setsuya Miyata, MD

Seirei Hamamatsu General Hospital

Hisayuki Okada, MD

Sendai Kousei Hospital

Naoto Inoue, MD

Sendai Open Hospital

St. Luke’s International Hospital

Atsushi Kato, MD Hidetaka Nakatani, MD Takayuki Toyama, MD Masaharu Okada, MD Yoichi Takeyama, MD Hiroshi Suzuki, MD Yuji Hamazaki, MD Hideki Nishimura, MD Masahiko Ochiai, MD Kazuhiro Ashida, MD Yutaro Nishi, MD

Sakakibara Heart Institute Sakakibara Heart Institute of Okayama

Setsunan General Hospital Shiga Medical Center for Adults Showa University Fujigaoka Hospital Showa University Hospital Showa University Northern Yokohama Hospital

St. Mary’s Hospital

Hideki Tashiro, MD

Tachikawa Medical Center

Minoru Takahashi, MD

Teikyo University Hospital

Ken Kozuma, MD

Participants

Doctors

Teine Keijinkai Hospital

Mitsugu Hirokami, MD

The Cardiovascular Institute The Jikei University Hospital Toho University Ohashi Medical Center Toho University Omori Medical Center Tohoku Koseinenkin Hospital Tokeidai Memorial Hospital Tokyo Medical University Hospital Tokyo Metropolitan Hiroo Hospital Tokyo Women’s Medical University Hospital Tomishiro Central Hospital Toranomon Hospital Tottori University Hospital Toyama Prefectural Central Hospital Toyama Red Cross Hospital Toyohashi Heart Center Tsuchiura Kyodo General Hospital Tsuchiya General Hospital Tsuyama Chuo Hospital Uwajima City Hospital Wakayama Medical University Hospital Yamagata Prefectural Central Hospital Yokohama City University Medical Center Yokohama Rosai Hospital Yokohama Sakae Kyosai Hospital Yokosuka General Hospital Uwamachi

Junji Yajima, MD Shunsuke Matsuno, MD Takayuki Ogawa, MD Kazuo Ogawa, MD Masato Nakamura, MD Hidehiko Hara, MD Kenji Wagatsuma, MD Hideo Nii, MD Yoshiaki Katahira, MD Tamon Yamanaka, MD Kazushi Urasawa, MD Katsuhiko Sato, MD Jun Yamashita, MD Yo Kimura, MD Tamotsu Tejima, MD Kota Komiyama, MD Atsushi Takagi, MD Osamu Arasaki, MD Sugao Ishiwata, MD Manabu Moriya, MD Osamu Igawa, MD Yoshiyuki Furuse, MD Kazuo Usuda, MD Yoshiki Nagata, MD Yutaka Nitta, MD Bunji Kaku, MD Kenya Nasu, MD Masashi Kimura, MD Tsunekazu Kakuta, MD Tetsumin Lee, MD Yasuhiko Hayashi, MD Nobuo Shiode, MD Issei Komatsubara, MD Masaki Yoshikawa, MD Kiyotaka Ohshima, MD Shuntaro Ikeda, MD Takashi Akasaka, MD Takashi Tanimoto, MD Motoyuki Matsui, MD Yoshiaki Tamada, MD Kiyoshi Hibi, MD Mitsuaki Endo, MD Kenichi Katoh, MD Kazuhiko Yumoto, MD Ichiro Michishita, MD Tsuyoshi Nozue, MD Takamasa Iwasawa, MD

Organization

Name

Institution

Principal Investigators (Steering Committees) Shinsuke Nanto, MD

Osaka University Graduate School of Medicine

Masato Nakamura, MD

Toho University Ohashi Medical Center

Toshiya Muramatsu, MD

Saiseikai Yokohama City Eastern Hospital

Hiroyoshi Yokoi, MD

Fukuoka Sanno Hospital

The Study Biostatistician

Yutaka Matsuyama, PhD

The University of Tokyo

Diabetes Mellitus Expert

Ryuzo Kawamori, MD

Graduate School, Juntendo University School

QCA

Toshiya Muramatsu, MD

Saiseikai Yokohama City Eastern Hospital

IVUS

Toshiya Muramatsu, MD

Saiseikai Yokohama City Eastern Hospital

CAS

Shinsuke Nanto, MD

Osaka University Graduate School of Medicine

Kyoichi Mizuno, MD

Nippon Medical School

OCT

Shinsuke Nanto, MD

Osaka University Graduate School of Medicine

Takashi Akasaka, MD

Wakayama Medical University

Tetsu Yamaguchi, MD

Toranomon Hospital

Tetsuya Sumiyoshi, MD

Sakakibara Heart Institute

Shoji Hori, MD

Osaka Medical Center

Imaging Substudy Investigator

Data Safety Monitoring Board (DSMB)

DSMB Biostatistician Biostatistician

Hiroshi Nonogi, MD

Shizuoka General Hospital

Masahiro Takeuchi, ScD

Kitasato University

Takaaki Isshiki, MD

Teikyo University Hospital

Takahiko Suzuki, MD

Toyohashi Heart Center

Clinical Event Committees (CEC)

Cerebrovascular Expert

Morimasa Takayama, MD

Sakakibara Heart Institute

Shinichi Toyama, MD

Yokohama Senin Hoken Hospital

Kazuo Kimura, MD

Yokohama City University Medical Center

Kazuhiro Hara, MD

Mitsui Memorial Hospital

Nobuyuki Komiyama, MD

Saitama Medical University of Medicine

Satoru Yoshida, MD

Yoshida Heart Clinic

Toshiro Kurosawa, MD

Machida Municipal Hospital

Junko Honye, MD

Fuchu Keijinkai Hospital

Kazuo Kitagawa, MD

Osaka University Graduate School of Medicine

Jeffrey J. Popma, MD

Beth Israel Deaconess Medical Center

Core Laboratory Angiographic Core Laboratory

Alexandra Popma Almonacid, MD IVUS Core Laboratory

Peter J. Fitzgerald, MD

Stanford University Medical Center

Yasuhiro Honda, MD Academic Research Organization Cardiovascular Imaging Core Laboratory CAS

OCT

Shigenori Ito, MD

Nagoya City East Medical Center

Junichi Kotani, MD

National Cerebral and Cardiovascular Center

Masamichi Takano, MD

Nippon Medical School Chiba Hokusoh Hospital

Takashi Tanimoto, MD

Wakayama Medical University

Masamichi Takano, MD

Nippon Medical School Chiba Hokusoh Hospital

Sponsor Non-profit organization Associations for Establishment of Evidence in Interventions (AEEI) QCA=quantitative coronary angiography ; IVUS= intravascular ultrasound ; CAS=coronary angioscopy ; OCT=Optical Coherence Tomography