Background RESULTS METHODS CONCLUSIONS ...

PaFerns of prostate cancer in men < 60 years of age Haitham Abdelmoteleb, Elisabeth Probst, John Iacovou Great Western Hospital, Swindon, UK

RESULTS

Background •  In the UK, the incidence rate of prostate cancer (PCa) in men aged 55-59 is 168 per 100,000 men. •  Between 2010 and 2012, an average of 74% of PCa deaths was in men aged 75 years and over, and more than 99% were in those aged 55 years and over. •  Age-specific mortality rates rise sharply from around age 55-59.

•  56 men met the inclusion criteria. •  Mean age: 56 + 4 years. •  Presentation: LUTS (33%), followed by rise in PSA (30.4%). •  Mean PSA: 22.9 + 57.2 ng/ml •  Risk Groups: Figure 1

•  Five-year survival for prostate cancer in men aged < 60 years is 92%.

•  Treatment Protocol: Figure 2

Treatment Protocol

METHODS

45.0%

40.0%

•  Retrospective analysis of our database.

35.0%

•  Period: January 2012 and December 2013.

AXIS TITLE

30.0%

25.0%

20.0%

•  Inclusion criteria: - < 60 years of age at presentation of PCa.

15.0%

10.0%

5.0%

0.0%

•  Exclusion criteria: - Previous diagnoses of Pca.

RALP

Treatment Protocol 41.0%

Radioth erapy 21.4%

Hormon al 7.1%

AS

HIFU

28.6%

1.8%

CONCLUSIONS Risk Groups

11%

32%

36%

•  In our center, we found that PCa in younger men tend to have a more advanced presentation.

Low Risk

•  Active surveillance as a management option should be considered with caution in this subgroup of men.

Intermediate Risk

21%

High Risk Locally Advanced

Figure 1

RESEARCH POSTER PRESENTATION DESIGN © 2015

www.PosterPresentations.com

REFERENCES 1.  Vickers et al. BMJ 2010;341:c4521 2.  Gallus et al. J Urol 2007;70:1121 3.  Forrest et al. Prost Canc Prost Dis. 2005;8:95

Date of preparation: February 2017 PHGB/MEDed/0816/0011z