The testing systems and processes we use ... Instron 55MT1 micro-torsion testing system, used to twist a sample under a
MPI Research
Biomechanical Testing
Biomechanics combines engineering with biology to help us better understand the complexities of life. Evaluating bone, cartilage, muscle, tendon, and other tissues—how they respond to a new type of procedure, drug or device—is the task of biomechanical testing. By understanding that interaction, researchers can devise new ways to enhance structural characteristics or make changes to materials to improve outcomes for patients. Whether you are looking to understand how conditioning of regenerative scaffolds influence in vivo outcomes or simply want to understand the fixation strength of a self-adhesive mesh, MPI Research has the specialized capabilities and experienced scientific staff to help our Sponsors succeed.
The testing systems and processes we use include three validated methods covering material indentation and force, material thickness, and material compression. Other capabilities cover push-out/pullout testing (for implant/screw interfaces), three- and four-point bend (for materials and long bones), ball burst and lap shear (for mesh integration/fixation), and a variety of compression, torsion, tensile testing methods used to evaluate bone, spine, tendon, muscle, and skin. So whether you are looking to do a small pilot or a complete GLP study, MPI Research stands ready to provide the support and expertise necessary to help our Sponsors succeed.
MPI Research
Validated Testing Systems • Instron 5500A: dual-column, table-top system for compression/extension of samples that yields mathematical data such as time, load, and distance to determine stress, strain, failure, and more • Instron 55MT1 micro-torsion testing system, used to twist a sample under a torsional force in order to determine the torsional properties of the sample Load vs. Extension
Compressive Load (N)
200 150 100 50 0
Compressive Load (N)
-50
200 180 160 140 120 100 80 60 40 20 0 -20
0
1
2
3
4
5
6
7
8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 Compressive Extension (mm)
Load vs. Time
0
1
2
3
4
5 6 Time (sec)
7
8
9
10
11
Study Types • Wound healing • Femur cortical bone implant • Long bone • Achilles tendon • Posterior lumbar fusion • Vertebrate • Osteochondral allografts • Hernia mesh Test Options • Ball burst testing • Lap shear testing • Push-out testing • Pull-out testing • Torsion testing • 3-Point bend • 4-Point bend • Compression testing • Tensile testing Animal Models • Rat • Rabbit • Canine • Swine • Sheep • Bovine
Micro-computed Tomography • Delivers exceptionally high-resolution microscopic images of biological samples • Allows evaluation of samples based on bone volume, density, trabecular and cortical bone morphometry • Study examples: canine dental implants, rabbit tibiofemoral joint arthritis models, rabbit posterior lumbar fusion imaging, and more
3D Analysis of Rodent Paranasal Sinus
Trabecular Analysis in A Rat MCLT Model
Taking You Further MPI Research Corporate Headquarters 54943 North Main Street Mattawan, MI 49071 USA
Tel: +1.269.668.3336 Fax: +1.269.668.4151 www.mpiresearch.com
[email protected] 7/15
