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MINERVA ANESTESIOL 2008;74:367-74
O R I G I N A L A RT I C L E
The ability of PiCCO versus LiDCO variables to detect changes in cardiac index: a prospective clinical study A. DONATI, R. NARDELLA, V. GABBANELLI, M. SCARCELLA, M. ROMANELLI, L. ROMAGNOLI, L. BOTTICELLI, S. PANTANETTI, P. PELAIA Anesthesia and In t e n s i ve Care Unit, De p a rtment of Ne u rosciences, Polytechnic Un i versity of Ma rche, Ancona, Italy
ABSTRACT Background. Both PiCCO and LiDCO can provide dynamic preload parameters, pulse pressure variation (PPV) and stroke volume variation (SVV). The PiCCO device also provides a measure of intrathoracic blood volume index (ITBVI). We investigated the agreement between SVV and PPV, as well as the reliability of LiDCO- and PiCCOmeasured SVV, PPV and ITBVI, in detecting fluid responsiveness before and after fluid challenge (FC). Methods. We performed a prospective clinical study in University Hospital ICU. Nine adult ICU patients with cardiovascular instability we re enrolled in the study. All patients we re sedated and mechanically ventilated with intermittent positive pre s s u re ventilation. The PiCCO and LiDCO systems we re both connected to each patient. T h e PiCCO pulse waveform system was joined by a 5-French (Fr) thermistor-tipped arterial catheter inserted into the femoral art e ry. LiDCO measurements we re performed through radial art e ry pulse contour analysis. Fluid challenge was performed using a rapid infusion of 7 mL/kg of 6% hydroxyethylstarch over 30 min. Results. Measurements of CI, ITBVI, SVV, and PVV were made using both techniques before and after FC. Pre-FC cardiac index (CI) measurements were similar with both devices, although the reading was higher after FC with the PiCCO device (P
