USING e-ANNOTATION TOOLS FOR ELECTRONIC PROOF CORRECTION Once you have Acrobat Reader open on your computer, click on the Comment tab at the right of the toolbar:
This will open up a panel down the right side of the document. The majority of tools you will use for annotating your proof will be in the Annotations section, pictured opposite. We’ve picked out some of these tools below:
1. Replace (Ins) Tool – for replacing text. Strikes a line through text and opens up a text box where replacement text can be entered. How to use it
2. Strikethrough (Del) Tool – for deleting text. Strikes a red line through text that is to be deleted. How to use it
Highlight a word or sentence.
Highlight a word or sentence.
Click on the Replace (Ins) icon in the Annotations section.
Click on the Strikethrough (Del) icon in the Annotations section.
Type the replacement text into the blue box that appears.
3. Add note to text Tool – for highlighting a section to be changed to bold or italic. Highlights text in yellow and opens up a text box where comments can be entered. How to use it Highlight the relevant section of text. Click on the Add note to text icon in the Annotations section. Type instruction on what should be changed regarding the text into the yellow box that appears.
4. Add sticky note Tool – for making notes at specific points in the text. Marks a point in the proof where a comment needs to be highlighted. How to use it Click on the Add sticky note icon in the Annotations section. Click at the point in the proof where the comment should be inserted. Type the comment into the yellow box that appears.
USING e-ANNOTATION TOOLS FOR ELECTRONIC PROOF CORRECTION
5. Attach File Tool – for inserting large amounts of text or replacement figures. Inserts an icon linking to the attached file in the appropriate place in the text.
6. Drawing Markups Tools – for drawing shapes, lines and freeform annotations on proofs and commenting on these marks. Allows shapes, lines and freeform annotations to be drawn on proofs and for comment to be made on these marks.
How to use it Click on the Attach File icon in the Annotations section. Click on the proof to where you’d like the attached file to be linked. Select the file to be attached from your computer or network. Select the colour and type of icon that will appear in the proof. Click OK.
How to use it Click on one of the shapes in the Drawing Markups section. Click on the proof at the relevant point and draw the selected shape with the cursor. To add a comment to the drawn shape, move the cursor over the shape until an arrowhead appears. Double click on the shape and type any text in the red box that appears.
J D V
13025
Journal Code
Manuscript No.
Dispatch: 13.2.15
CE: Vanitha
No. of pages: 2
PE: Sudhakar S
JEADV
LETTER TO THE EDITOR
Editor Hair removal with lasers and intense pulsed light (IPL) devices have become a mainstay in many physicians’ offices and nonmedical settings (e.g. beauty parlours) all over the world. The great demand for photo-epilation techniques and the ability to cut costs has led to the development of home devices.1 Acne vulgaris, rosacea and photo rejuvenation are further advertised indications for home use. Many devices are available in the market, although only a few have undergone controlled clinical trials to document their safety and efficacy.2 The evidence available from prospective uncontrolled clinical trials indicates that the home-use light-based devices currently available are efficacious in short-term hair removal.3 Of note, most IPL home devices in these studies have been used under medical supervision and/or the studies have been sponsored by the industry itself. Skin pigmentation has already been identified as an independent risk factor for side-effects in low-fluence IPL 4 whereas other studies endorse IPL home treatment for all skin types.5 According to the manufacturers, protective eyewear is not required because the light generated is self-contained within the home device; however, this must be regarded as an additional risk factor for ocular damage in handling all cases.2 Other potential adverse events of IPL home treatment include oedema, pain, erythema, hyper- and hypo-pigmentation, scarring, blistering, crusting, burning, or even paradoxical hair growth. Sufficient safety instructions are often missing or incomplete in the manuals, so users are not made aware of possible complications. Additionally, the lack of individual verbal informed consent generally leads to uncritical application and unrealistic expectations of the user. We report the case of a 25-year-old Caucasian female with Fitzpatrick Phototype III. She presented with complications following her initial hair removal session using an IPL home device (Rio IPL 8000TM; Dezac Group, Cheltenham, UK). As an adverse effect, the site treated on the lower leg showed blistering and crusting which had lasted for 2 weeks (Figs 1 and 2). No scarring was seen during the course of the treatment, but hyperpigmentation is still present after a follow-up period of twelve months. The settings used were the lowest standard defaults. There was no extensive sun exposure before and/or after treatment. In our case, the sources of error probably included the lack of cooling, and too many treatment passes. In addition, a too high energy density has to be discussed; however, according to the
JEADV 2015
COLOR
Are IPL home devices really 1 foolproof?
Figure 1 Xxxxxx.
Blistering and burning after initial hair removal session with an IPL home device on the lower leg.
4
COLOR
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
Figure 2 Xxxxxx.
patient the fluence was set at the lowest possible default. A test treatment had not been conducted either, which is indicated especially in treating larger areas such as on the lower leg. Also, the device user did not have a medical supervision during the (initial) treatment and/or an individual instruction. To our knowledge, this is the first report with a complication of an IPL home device. Our objective was to show that IPL home devices are not as safe as they purport to be. As in the case with
© 2015 European Academy of Dermatology and Venereology
Letter to the Editor
2
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52
professional systems, there is a thin line between achieving the appropriate therapeutic dose and the manifestation of harmful complications. IPL home devices have received US Food and Drug Administration (FDA) clearance for permanent hair reduction. Nevertheless, it is our conviction that laser and IPL systems should not be used in home devices without the support and supervision of a medical professional, and under no circumstances they are to be seen as harmless cosmetic products. L. Schmitt,1 K. Rezai,2 S. Karsai3,4,*
2 1
3
Dermatology clinic, Bremserstr. 79, Ludwigshafen 67063, 2Dermatology €nster, Windhorststr. 16, Mu €nster 48143, 3Dermatology clinic, Practice Mu Heidelberger Landstr. 379, Darmstadt 64297, 4Dermatology clinic, University of Greifswald, Ferdinand-Sauerbruchstr., Greifswald 17475, Germany *Correspondence: S. Karsai. E-mail:
[email protected]
JEADV 2015
References 1 Alster TS, Tanzi EL. Effect of a novel low-energy pulsed-light device for home-use hair removal. Dermatol Surg 2009; 35: 483–489. 2 Town G, Ash C. Are home-use intense pulsed light (IPL) devices safe? 5 Lasers Med Sci 2010; 25: 773–780. 3 Thaysen-Petersen D, Bjerring P, Dierickx C, Nash JF, Town G, Haedersdal M. A systematic review of light-based home-use devices for hair removal and considerations on human safety. J Eur Acad Dermatol Venereol 2012; 26: 545–553. 4 Thaysen-Petersen D, Lin JY, Nash J et al. The role of natural and UV-induced skin pigmentation on low-fluence IPL-induced side effects: a randomized controlled trial. Lasers Surg Med 2014; 46: 104–111. 5 Garden JM, Zelickson B, Gold MH, Friedman D, Kutscher TD, Afsahi V. Home hair removal in all skin types with a combined radiofrequency and optical energy source device. Dermatol Surg 2014; 40: 142–151. DOI: 10.1111/jdv.13025
© 2015 European Academy of Dermatology and Venereology
Author Query Form Journal: Article:
JDV 13025
Dear Author, During the copy-editing of your paper, the following queries arose. Please respond to these by marking up your proofs with the necessary changes/additions. Please write your answers on the query sheet if there is insufficient space on the page proofs. Please write clearly and follow the conventions shown on the attached corrections sheet. If returning the proof by fax do not write too close to the paper’s edge. Please remember that illegible mark-ups may delay publication. Many thanks for your assistance. Query reference
Query
1
AUTHOR: Please note that no additional changes will be accepted after your corrections are submitted.
2
AUTHOR: Please confirm that given names (red) and surnames/family names (green) have been identified correctly.
3
AUTHOR: Please check and provide the organization name for the affiliations ‘1’, ‘2’, and ‘3’.
4
AUTHOR: Please provide a suitable legend for Figures 1 and 2.
5
AUTHOR: References [2] and [6] are identical. Hence, reference [6] is deleted and rest of the references is renumbered. Please check.
Remarks
Answers Query 1: We note, that no additional changes will be accepted after the submitted corrections Query 2: Given names and family names have been identified correctly Query 3: The affiliations are correct Query 4: A legend has been provided for figure 1. Please delete figure 2. Query 5: References have been renumbered correctly. Please provide the word „initial“ in the last sentence of the article into „Nevertheless, it is our conviction that laser and IPL systems should not be used in home devices without the initial support and supervision of a medical professional, and under no circumstances they are to be seen as harmless cosmetic products.“ Thank you!
