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Fox BD [170]. 2012 BMJ. 3. ... Lopez-Olivo MA [183]. 2012 JAMA .... review and meta-analysis of randomised trials. BMJ. 2017;358:j3887. 17. Batelaan NM .... Khera R, Murad MH, Chandar AK, et al. ..... Keene D, Price C, Shun-Shin MJ, et al.
pressure (mmHg). Yes/No. Heart rate per minute. Yes/No. Consciousness. Yes/No. Oxygenation: NRM. Ventimask O2-glasses. None. Oxygen in liters per minute ...
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Abbreviations used: AD = Alzheimer's disease; BMI = body mass index; SD = standard deviation; T2DM = Type 2 diabetes mellitus; examination parameter total ...
Institute for Biomedical Technologies, CNR, Bari, Italy. 7 Laurent ... Instituto Gulbenkian de Ciencia, Centro Portugues de Bioinformatica, Oeiras, Portugal.
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folder holding the TIFF microscopy images and an output folder for the generated data can be selected. The 'White', 'Red' and 'Green' fluorescence microscopy ...
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Search Procedure for the Systematic. Review. Databases used for Initial Search. Ovid MEDLINE (R) In-Process and other Non-Indexed Citations (January 17th.
General Procedure for Peptide Coupling (GP 1): HOBt (2.6 mmol), Et3N (3.0 mmol), DCC (2.6 mmol), and. DMAP (0.1 mmol) were sequentially added to a stirred ...
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Shivashankar H Nagaraj , Aaron Ingham and Antonio Reverter. Additional file 1. Table S1. Summary of the significant relationships between the gene attributes: ...
Cui R, Suemaru K, Li B, Kohnomi S, Araki H (2009) Tropisetron attenuates naloxone-induced place aversion in single-dose morphine-treated rats: role of alpha7 ...
Additional File 1 Additional File 1. Overview of the ...
16 moderate phenotype. 0. 19. 19. 2 weak phenotype. 0. 25. 5. 1 normal. 8. 45. 8. 0 phenotypes in surviv. 0%. 71%. 92%. 100%. Tcf3. P. N. A. Tcf3. MO. Tcf3. kP.
Additional File 1
Tcf3MO
Tcf3kPNAmut
Tcf3kPNA
Tcf3PNA+Tcf3spPNA
Tcf3spPNA
Tcf3PNA
concentration [µM]
0
50
100
200
400
600
900
1200
200+200
300+300
400+400
600+600
number of embryos dead death rate
17 1 6%
72 5 7%
72 2 3%
110 10 9%
123 8 7%
52 3 6%
90 34 38%
strong phenotype moderate phenotype weak phenotype normal phenotypes in surviv.
0 0 0 16 0%
0 3 12 52 22%
2 7 18 43 39%
10 12 29 49 51%
15 17 33 50 57%
3 10 15 21 57%
24 12 12 8 86%
number of embryos dead death rate
45 2 4%
32 2 6%
34 2 6%
59 3 5%
101 21 21%
83 7 8%
55 49 89%
strong phenotype moderate phenotype weak phenotype normal phenotypes in surviv.
0 0 0 43 0%
0 0 2 28 7%
0 1 2 29 9%
2 5 10 39 30%
11 8 20 41 49%
6 11 18 41 46%
1 1 3 1 83%
number of embryos dead death rate
37 1 3%
45 1 2%
93 15 16%
121 17 14%
42 30 71%
strong phenotype moderate phenotype weak phenotype normal phenotypes in surviv.
0 0 0 36 0%
2 7 13 22 50%
20 18 14 26 67%
24 19 34 27 74%
2 0 9 1 92%
number of embryos dead death rate
19 3 16%
47 7 15%
48 7 15%
45 8 18%
92 18 20%
78 33 42%
42 30 71%
strong phenotype moderate phenotype weak phenotype normal phenotypes in surviv.
0 0 0 16 0%
15 6 4 15 63%
6 6 19 10 76%
6 11 12 8 78%
26 26 16 6 92%
21 10 11 3 93%
7 0 0 5 58%
number of embryos dead death rate
25 3 12%
24 2 8%
46 7 15%
49 8 16%
53 17 32%
strong phenotype moderate phenotype weak phenotype normal phenotypes in surviv.
0 0 0 22 0%
0 0 0 22 0%
0 0 2 37 5%
1 1 3 36 12%
0 1 3 32 11%
number of embryos dead death rate
9 1 11%
171 17 10%
112 14 13%
34 15 44%
strong phenotype moderate phenotype weak phenotype normal phenotypes in surviv.
0 0 0 8 0%
65 19 25 45 71%
66 19 5 8 92%
16 2 1 0 100%
Additional File 1. Overview of the PNA and MO induced loss of function phenotypes. Embryos at the 1-cell stage were injected with PNAs or MOs at the indicated concentrations. Phenotypes were categorized according to the size of the eyes into: weak, slightly smaller eyes; moderate, smaller eyes; strong, eye-less. Abbreviations: PNA, peptide nucleic acid; MO, morpholino oligonucleotides.
